20xx年醫(yī)學(xué)專題—crrt：嚴(yán)重膿毒癥與mods(邱海波)-預(yù)覽頁
【正文】 derstanding Renal Replacement Therapy and Acute Renal Failure in the ICU (The B.E.S.T kidney study),第三頁，共四十四頁。,IHD vs CRRT,ICU RRT n=116,RRT for overdose n=7,Preexisting CRF n=16,ICU RRT for ARF/MOF n=66,Initial CRRT n=66,Initial IHD n=28,Jacka MJ, Ivancinova X, Gibney RTN. Can J Anaesth 2005。i)壓下降，導(dǎo)致腎臟低灌注，加重腎臟缺血性損傷，延遲急性腎衰竭腎功能的恢復(fù),為什么CRRT促進(jìn)(c249。 0.5 L Everyotherday: 3.5 177。 2 days Everyotherday:16 177。,Effect of RRT dose on recovery of renal function?,P = NS,Ronco C et al. Effects of different doses in CVVH on outcomes of ARF:A prospective RCT,Lancet 2000。 34: 424 432 Mehti. RL. Collaborative Group for Treatment of ARF in ICU:A RCT of continuous versus IHD for ARF. Kidney Int 2001。nzhě)的影響 －CRRT可降低危重病患者病死率,Quality score 5: definitely equal,第十一頁，共四十四頁。,1989－1997：100例創(chuàng)傷(chuāngshāng)后ARF 早期－后期的臨界：BUN 60mg/dl 兩組病人創(chuàng)傷評分、GCS、發(fā)生休克的比例、年齡、性別和創(chuàng)傷分布均無差異,早期－后期(h242。ngxiǎn)差異,Gettings LG. Intensive Care Med, 1999, 25: 805813,Outcome Early start 39% survival Late start 20% survival,第十五頁，共四十四頁。 2436 L/24 h),Bouman et al. Crit Care Med 30:22052211, 2002,第十六頁，共四十四頁。1.9,n=35 SOFA 10.1177。 356: 26 30,第十九頁，共四十四頁。,160 pats with ARF: Daily vs everyotherday ID,N Engl J Med 2002。 If hemodynamically unstable (SOFA CVS score: 34) CVVHDF at 20 ml/kg/hr or SLED 3times/week (target Kt/V = 1.21.4/session),第二十四頁，共四十四頁。 zh236。nli224。,Mean Norepinephrine Dose,Mean C3a concentration,Mean C5a concentration,第三十頁，共四十四頁。)預(yù)后,第三十二頁，共四十四頁。r qiě)對溶質(zhì)動力學(xué)無明顯改進(jìn) Ranco提出了脈沖式高容量血液濾過,Seminars in Dialysis, 2006, 19(1): 6974,第三十三頁，共四十四頁。ng)的可能途徑,1,2,第三十六頁，共四十四頁。)清除/遏制炎癥反應(yīng)的可能途徑,第三十八頁，共四十四頁。)血流動力學(xué)的影響 Hemodynamic response to coupled plasmafiltrationadsorption in human septic shock,N=12 mechanically ventilated pats with septic shock Intervention: A median of 10 consecutive sessions (prescribed treatment time: 10 h/session。,Thanks for you attention,第四十三頁，共四十四頁。CRRT對ARF腎功能恢復(fù)的影響 －CRRT促進(jìn)腎功能恢復(fù)。)的比例、年齡、性別和創(chuàng)傷分布均無
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