20xx年醫(yī)學(xué)專題—北京上海胃食管反流癥狀的流行病學(xué)調(diào)查(精)-全文預(yù)覽
【正文】 0433 【Abstract】 Objective To explore the one yearpoint prevalences (JulSep,1996) of symptomatic gastroesophageal reflux (GER), gastroesophageal reflux disease (GERD) and reflux esophagitis (RE) among adult population in Beijing and Shanghai and to identify the risk factors of GERD. Methods 5 000 residences of the two cities, age between 1870 were studied through questionaire. Study was done by clustering sampling from city, surburban and rural areas using simple random sampling. Symptom scores (Sc) of the intensity and frequency of heartburn, acid reflux and regurgitation within one year at the time of study were taken as indices of acid reflux (highest Sc=18) and Sc≥6 indicated the presence of symptomatic GER. A case control study was also performed in some subjects from the survey to confirm the diagnosis of GERD and RE using gastroscopy and 24h pH monitoring. An estimation of the prevalence of GERD and RE was made on the basis of correct diagnostic rates of the diseases. Results (1) 4 992 subjects pleted the survey, % of the people had heartburn once a day, 448 people accounted for % of the population screened had symptomatic GER (Sc≥6), and male to female ratio was 1∶. Estimated prevalences for GERD and RE were % and % respectively. (2) Stratified analysis indicated that the prevalence of symptomatic GER in Beijing (%) was higher than that in Shanghai (%), and there was also a higher prevalence of GER in male, in laboring people and in people of rural areas in Beijing as pared with Shanghai. (3) Logistic analysis indicated that GER had a close relatioship with dental, pharnyngolaryngeal disorders and respiratory diseases, such as asthma and bronchitis, etc. Conclusions GERD is different in the northern and southern area of China. Ratio between GERD and RE is 3∶1 in our study.
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