【正文】
.01)關(guān)鍵詞:馬采酸氯笨那敏片;溶出度:分量均勻度;紫外分光光度擊Comparison of the Dissolubility of Chlorphenamine Maleate Tablets Produced by 4 Different FacloriesZKNG I),.enjie.JIN(:Li,SUN Weizhang,ZHANG Iic(Dept of Pharmacy,Chengdu(]eneral Hospital of Chgdu Milita]、’C、Ol:lll[talld、Chengdu 610083)|,BSTR^CT:()BJE(TI、1F:’I39。le tllo d1‘solubmtv()f four kinds of domestlc conlnlercial chic,rphen;i』I】1Ile Ine】o“112 lablc【h 1)v paddlemethod and to analyc the dissolulilm pa ramelers,【168。Ill】PaIP.dlsc,ol/ibllitv COl31t tinIformltv,UV specl rop]lolonlcI TV馬柬酸氯苯那敏為馬米酸氯苯吡胺的馬來酸鹽.是重要的丙胺類抗組胺藥.臨床鹿用下R當(dāng)廣泛。DU 640型分光光度計(jì)(美幽嘰克曼公_J);ZRS 4智能蒲出過驗(yàn)儀f天津大學(xué)無線電廠)。2.3 含量均勻度測定表2 不同時(shí)間藥物的累積釋放百分率(%}廈溶出參數(shù)(n=61“ 5 15 ZT, 35 41 Ft r168。組㈣變異綹內(nèi)蹙芹m 組間空異109.