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Cardiol 2007。 7:212.,TABLE 2. Risk of Sudden Cardiac Death,Risk of Sudden Cardiac Death,Saxon LA et al. Circulation. 2006。1:6371,Proliferative signaling pathways that mediate cardiac hypertrophy,。346:87783.,Defibrillator,Conventional,P = 0.007,1.0,0.9,0.8,0.7,0.6,0.0,Probability of Survival,0,1,2,3,4,Year,No. At Risk Defibrillator 742 502 (0.91) 274 (0.94) 110 (0.78) 9 Conventional 490 329 (0.90) 170 (0.78) 65 (0.69) 3,Nonpharmacological Physical activity tailored to individuals Walk Slow walking at home 1030 min a day, 7 days a week Class IV patients require gentle mobilisation as symptoms allow Bed rest for those with acute deterioration of symptoms,Nonpharmacological Sodium restriction 3 g sodium/day No more than 2 L fluid intake per day Daily weighing Weight variation should be 2 kg in two consecutive days,Katz, A. M. Circ Heart Fail 2008。49:963971,Death After a Nonfatal Myocardial Infarction or Nonfatal Stroke,CCBs: NHF recommendations,Amlodipine and felodipine can be used to treat comorbidities such as hypertension and CHD in patients with systolic CHF They have been shown to neither increase nor decrease mortality. Nondihydropyridine calciumchannel blockers such as verapamil and diltiazem are contraindicated in patients with systolic heart failure,Electromechanical dysfunction,Defined as any abnormality in the generation or transmission of electrical impulses that results in clinically significant alteration in the mechanica