usp中緩沖溶液和標(biāo)準(zhǔn)溶液及詳細(xì)配制方法-文庫(kù)吧
2025-08-06 13:17 本頁(yè)面
【正文】 hange in ion activity. It isdefined as the ratio of acid or base added (in gramequivalents perliter) to the change in pH (in pH units). The capacity of a bufferedsolution is adjusted to the conditions of use, usually by adjustment ofthe concentrations of buffer substances.Buffers are used to establish and maintain an ion activity withinnarrow limits. The most mon systems are used to establishhydrogenion activity for the calibration of pH meters, in thepreparation of dosage forms that approach isotonicity, in analyticalprocedures, and to maintain stability of various dosage forms.Buffers used in physiological systems are carefully chosen so as not tointerfere with pharmacological activity of the medicament or normalfunction of the organism. It is essential that buffers used in chemicalanalysis be patible with the substance determined and the reagentsused.STANDARD BUFFER SOLUTIONS Standard solutions of definite pH arereadily available in buffer solutions prepared from the appropriatereagents. In addition, buffer solutions, buffer tablets, and buffersolid
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