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【正文】 PS are secreted by type II epithelial cells of pulmonary alveoli. Dipalmitoyllecithin( DPPC) is the main substance. Surfactant protein( SP) PS are produced from 18~20w till 35~36w when lung is mature. Etiology PS cover the inner surface of pulmonary alveoli, which can: ? decrease alveolar surface tension ? prevent alveoli collapse at the end of expiration ? keep functional residual capacity( FRC) ? keep stable pulmonary alveolus pressure ? decrease fluid exude from capillary to pulmonary alveoli Etiology Preterm birth pH of body fluid, body temperature, volume of pulmonary blood flow and hormone can influence PS secretion. Asphyxia, hypothermia, placenta previa, placental abrup
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