篇第九章白血病ppt課件(已改無錯字)
2023-02-05 15:39:18 本頁面
【正文】 胞 B 細胞（ 4%） B 細胞前體 CD7（敏感）， cCD3 （特異） CD19 (敏感 ), cCD79a (特異 ) 成熟 T 細胞 （ 18%） 前 T 細胞（ 6%） 前 B細胞 （ 9%） 早期前 B 細胞 （ 52%） 前 前 B 細胞 （ 11%） sIg?, sIg? Insert table 90% of the cases with leukemia have nonrandomized translocation P118 types of translocations CML AMLM2 AMLM3 AMLM4 AML AMLM4E0 Other new developed methods Differential Diagnosis Pseudoleukemia Myelodysplastic syndrome Nonleukemic pancytopenia Treatment 1. Supportive cares and preparation of the patients 2. Antileukemic therapy 3. Therapy of the central nervous system 4. Stem cell transplantation Anemia Hemorrhage Infection Hematological support Transfusion of Platelets Transfusion of packed red cells Transfusions of granulocytes Transfusions of IgG Infection control Special precautions: protective isolation Elimination of contaminated foods Oral and digestive system care Broad spectrum antibiotics GMCSF administration Antileukemic therapy Chemotherapy to kill leukemia cells using strong anticancer drugs Treatment phases Induction therapy: the aim is to bring about remission , that is leukemic cells are no longer found in the bone marrow and the recovery of normal hematopoiesis Postremission therapy: to eliminate any leukemia cells potential hiding in the body Special subtypes Acute promyelocytic Leukemia (APL): because of the small particles (procoagulants) inside the APL cell, DIC are monly seen in this type of AML Normal APL Genes essential for differentiation are shut down by the fusion
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