丙型肝炎的疫苗研究現(xiàn)狀-閱讀頁
2024-10-04 12:39本頁面
【正文】 45.2. Mart237。llberg M, Frelin L, Weiland O. DNA vaccine therapy for chronic hepatitis C virus (HCV) infection: immune control of a moving target. Expert Opin Biol Ther. 2009, 9(7): 805 815.6. Zhu Q, Guo JT, Seeger C. Replication of hepatitis C virus subgenomes in nonhepatic epithelial and mouse hepatoma cells. J virol, 2003, 77(12): 9204 9210.7. Lagging LM, Meyer K, Hoft D, et al. Immune responses to plasmid DNA encoding the hepatitis C virus core protein. J virol, 2005, 69(9): 5859 5863.8. Rollier C, Depla E, Drexhage JA, et al. Control of heterolozous hepatitis C virus infection in chimpanzees is associated with the quality of vaccine induced peripheral Thelper immune response. J virol, 2004, 78(6): 187196.9. Ara Y, Saito T, Takagi, et al. Zymusan enhances the immune mspouse to DNA vaccine for human immunodeficiency virus type1 through the activation of plement system. Immunology, 2001, 103(1): 98 105.10. Lang KA, Yan J, DraghiaAkli R, et al. Strong HCV NS3 and NS4Aspecific cellular immune responses induced in mice and Rhesus macaques by a novel HCV genotype 1a/1b consensus DNA vaccine. Vaccine. 2008, 26(49): 6225 6231.11. 內(nèi)容總結(jié)
12. （1）丙型肝炎的疫苗研究現(xiàn)狀
摘要： 丙型肝炎病毒（hepatitis C virus, HCV）是引起輸血相關(guān)肝炎及慢性肝炎、肝硬化、肝癌的主要病原，目前尚無有效的治療與預(yù)防手段
（2）主要有C區(qū)DNA疫苗、E區(qū)DNA疫苗、C+E區(qū)DNA疫苗、Ns區(qū)DNA疫苗等
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