分子生物學緒論(1)-閱讀頁
2025-02-02 00:40本頁面
【正文】 ganelle isolation） Cross with Cell Biology （核） DNA 復制（ replication） ? RNA轉錄（ transcription） amp。 Covalent(共價 ) or noncovalent associations of more than one major classes of large biomolecules which greatly increases the functionality or structural capabilities of the plex. 核蛋白 Nulceoprotein: nucleic acids + protein (Section A4) A3 Macromolecules 糖蛋白 Glycoprotein: carbohydrate + protein 脂蛋白 Lipoprotein: Lipid + protein A4 大分子的組裝 Protein plexes (蛋白質復合體 ) Nucleoprotein (核蛋白 ) Membranes (膜 ) Noncovalent interactions 非共價相互作用 protein plexes 蛋白質復合體 Long polymers of tubulin維管蛋白 . Schematic diagram showing the (a) crosssectional and (b) surface pattern of tubulin a and b subunits in a microtubule (microfilament) actin and myosin, ponents of muscle fibers as well keratin (cilia纖毛 and flagella鞭毛 ) A4 Large macromolecular Assemblies Noncovalent interaction 角蛋白 Crystal structure of 50S rRNA A4 Large macromolecular Assemblies Nulceoprotein 核蛋白 (1) associations of nucleic acids and protein Ribosome核糖體 : ribosomal proteins ＋ rRNAs ?Chromatin (染色質 ): ?Viruses: ?Telomerase (端粒酶 ) : ?Ribonuclease P： A4 Large macromolecular Assemblies DNA + 組蛋白 蛋白衣殼 + RNA or DNA 復制染色體末端 . RNA 作為復制模板 蛋白質 (催化 )合成反應 tRNA 突變 . Protein P ＋ RNA Nulceoprotein核蛋白 (2) Plasma membrane 質膜 Noncovalent非 共價 interactions The force of macromolecule assembly 大分子組裝的力 A4 Large macromolecular Assemblies 范德華力 van der Waals forces: noncovalent associations between uncharged molecules. *氫鍵 Hydrogen bonds (dipoledipole): nucleic acids *疏 水作用力 Hydrophobic interaction: proteins 電荷 電荷作用（鹽橋） : 帶電分子 電荷 偶極 ,偶極 偶極 :至少一方是一個偶極 .力弱
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