心血管活動的體液調(diào)節(jié)-在線瀏覽
2025-03-09 05:34本頁面
【正文】 ition , the increase in the level of ADH in plasma firstly induces the effect of antidiuresis,and only when its level increases definitely ,the BP increases. ADH plays an important role in the regulation of the volume of extracellular fluid .Under the condition of water bearing , water depletion and blood loss ,the secretion of ADH increases to keep the normal volume of body fluid and maintain the normal BP. 正常情況下，血漿中 ADH濃度升高時首先出現(xiàn)抗利尿效應(yīng)，當(dāng)其血漿濃度明顯升高時，才引起血壓升高。在禁水、失水、失血等情況下， ADH釋放增加 ,保留體內(nèi)液體量，維持動脈血壓。 ? 1980年 佛奇戈特 (Furchgott) 推測 Ach通過內(nèi)皮細胞釋放的 EDRF來實現(xiàn)其舒血管效應(yīng) 。 Physical function of NO NO的生理作用 AC NOS 血管舒張 精氨酸 NO cGMP↑ [Ca2+]i↓ 瓜氨酸 ↑ NOS 活性： Ach， 緩激肽， P物質(zhì)， 5－ HT,ATP ↓ NOS 活性： NA， ADH， AII Endothelin 內(nèi)皮素（ ET) 21肽 Vascular endothelial cell excretes , strong vasoconstrictor. 血管內(nèi)皮細胞分泌的強縮血管物質(zhì)。 (2) Endotheliumderived vasoconstrictor substances 血管內(nèi)皮生成的縮血管物質(zhì) 5. Atrial natriuretic peptide (ANP) 心房鈉尿肽 (ANP) Synthesis position:atrial muscle cell (28 peptides) 合成部位：心房肌細胞， 28肽 Target an: heart, blood vessels, kidney, CNS 靶器官：心臟，血管，腎臟，中樞 The blood volume increases, the atrium wall stretches →ANP↑ . 血容量增加，心房壁受到牽拉 →ANP↑ 。 ? The blood vessel dilates and the peripheral resistance increases. 血管舒張，外周阻力 ↑ 。 ? To inhibit the secretion of ADH . 抑制血管升壓素的釋放。激肽可使血管平滑肌舒張和毛細血管通透性增高，但在其他平滑肌則引起收縮。 1. Active hyperemia 主動充血 The phenomenon of the increase in the blood flow in most ans and tissues when their metabolism activity strengthen is called active is caused by the relaxation of arterioles as a result of the activity of ans and tissues strengthen. 大多數(shù)器官和組織代謝活動增強時表現(xiàn)為血流量增加，稱為主動充血。 The relaxation of arteriole is the result of the change of the concentration of the chemical reconstituent in extracellular fluid,which includes the decrease in OPP, the increase in the concentration of CO2, H+, adenosine, ATP etc.
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