優(yōu)質(zhì)文檔]動(dòng)脈硬化血栓病理心理學(xué)-在線瀏覽
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【正文】 n the US if patients were given appropriate care. National Committee for Quality Assurance. Washington, DC 2022.700Cervicalcancer screeningPrenatal care?blocker treatmentBreastcancer screeningSmoking cessationCholesterol managementDiabetes careHighblood pressure control1500170025002700650013,60028,300瓤砧附落鹼呸原掀衡狀覽姑驗(yàn)蕭判惱批羊程著誡嗆毀萬(wàn)酵熾蹤一持隕鬧縫動(dòng)脈硬化血栓病理生理學(xué)動(dòng)脈硬化血栓病理生理學(xué)*Based on data from the ARIC study of the National Heart, Lung, and Blood Institute, 19871994. Includes Americans hospitalized with definite or probable MI or fatal CHD, not including silent MIs. ACS, acute coronary syndrome。 ARIC, Atherosclerotic Risk in Communities, CHD, coronary heart disease. American Heart Association. Heart Disease and Stroke Statistics—2022 Update.Epidemiology of ACS in the United States ? Single largest cause of death? 515,204 US deaths in 2022? 1 in every 5 US deaths? Incidence? 1,100,000 Americans will have a new or recurrent coronary attack each year and about 45% will die*? 550,000 new cases of angina per year? Prevalence? 12,900,000 with a history of MI, angina, or both哎鎮(zhèn)奸焙族熟西恿熟鮮痰羌價(jià)論宣淡蹈謠芹蘇錫刻窘粒嗅琶駒陵羅柒磺隴動(dòng)脈硬化血栓病理生理學(xué)動(dòng)脈硬化血栓病理生理學(xué)Epidemiology of Stroke in the United States? Prevalence? million cases? Incidence? 700,000 new or recurrent strokes each year? Morbidity/mortality? Third leading cause of death? 1 of every 14 deaths (?168,000 deaths)? Stroke: a leading cause of longterm disabilityAmerican Heart Association. Heart Disease and Stroke Statistics—2022 Update.丟瑯虜妻醋級(jí)挨波曲剛份忙蘿盅舞惹恩疲裹拾潮柵等龐蟄艇蒲恍讓灶袱勇動(dòng)脈硬化血栓病理生理學(xué)動(dòng)脈硬化血栓病理生理學(xué)Peripheral Arterial Disease ? PAD affects 12% of the adult population1,2? 20% of the population aged 70 ? Associated with 6fold increase in CV mortality3? Underrecognized and undertreated4? Measurement simple, inexpensive, and noninvasive? Appropriate for risk assessment and screening? Patients at high risk need aggressive riskfactor modification and antiplatelet drugs4PAD, peripheral artery disease。 91:14721479.3 Criqui MH, et al. N Engl J Med. 1992。286:13171324.囑勃隴掩滬漫趟馭瓷謙庇艷騷荔詫榨回卜救蟬蝎涎奔斜埋屜碼忌睬縷甥潘動(dòng)脈硬化血栓病理生理學(xué)動(dòng)脈硬化血栓病理生理學(xué)Diabetes: Impact in United States? 12 million people with diabetes1? Diabetes is the 5th leading cause of death1? Half of diabetic patients will experience kidney failure1? Diabetes is the leading cause of new adult cases of blindness2? Direct and indirect diabetes costs were estimated at $132 billion1 in 2022 1 American Diabetes Association. Diabetes Care. 2022。31:S16.Coronary DiseasePAD12%33%15%5% 14%13%8%Cerebral DiseaseCoronary DiseasePAD19%30%25%4% 12%7%3%Cerebral DiseaseCAPRIE Aronow amp。 PAD, peripheral arterial disease。47:12551256. Schafer AI. Am J Med. 1996。 TIA, transient aschemic attack, PAD, peripheral artery disease.Adult Treatment Panel II. Circulation. 1994。1:333339.Wilterdink, JI, et al. Arch Neurol. 1992。326:381386.箭貸擊柬挺于嘻撤擯紐理砌癡涎龐籬乳紙拈僑都佐喂怒綿蕾礙肯啦渝惦翰動(dòng)脈硬化血栓病理生理學(xué)動(dòng)脈硬化血栓病理生理學(xué)UnstableanginaMI Ischemic stroke/TIACritical legischemiaIntermitentclaudicationCV deathACSAtherosclerosisStable angina/ Intermittent claudicationAtherothrombosis: A Generalized and Progressive ProcessThrombosisAdapted from Libby P. Circulation. 2022。92:657671.慢塌從伎假院蛀柱爛苔識(shí)痰糕絞甘酞棉爵廳例呻遜遂既擺壤饒販禾頹否大動(dòng)脈硬化血栓病理生理學(xué)動(dòng)脈硬化血栓病理生理學(xué)Characteristics of Unstable and Stable PlaqueThin fibrous capInflammatory cellsFewSMCsErodedendotheliumActivatedmacrophagesThickfibrous capLack ofinflammatory cellsFoam cellsIntactendothelium MoreSMCsLibby P. Circulation. 1995。326:310318.Falk E, et al. Circulation. 1995:92:657671.Cap Thickness/ Consistency蛛稍薯膘撣苯磕友撅斡
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