20xx年醫(yī)學(xué)專題—肉毒毒素在神經(jīng)源性疼痛中的應(yīng)用-展示頁
2024-11-14 12:03本頁面
【正文】 機制,The pathophysiological mechanisms that underlie NP are not fully understood. Several hypotheses have been suggested including ： (1) sensitization of nociceptors (2) abnormal ectopic excitability of affected neurons (3) disinhibition of nociception control at the spinal level network (4) sympathetically maintained pain (5) CNS reorganization processes,第七頁，共三十三頁。)過敏 (Hyperalgesia) －對疼痛剌激反應(yīng)增高或持久劇痛,第六頁，共三十三頁。 fū)上無客觀原因異常感覺 感覺遲鈍(dysesthisias),(與刺激有關(guān),在檢查期間引出) 異常性疼痛(Allodynia) －對正常無痛刺激感到疼痛 痛覺(t242。ngt242。) “周圍或中樞神經(jīng)系統(tǒng)原發(fā)性或繼發(fā)性損害或功能障礙或短暫紊亂引起的疼痛”,Neuropathic pain (NP) is caused by structural lesion leading to functional abnormalities in the central and peripheral nervous system. It is a frequent disorder, and its prevalence is estimate to be between 6.9% and 10% in the general population [3].,第五頁，共三十三頁。ng)疼痛(NP),國際疼痛研究會(IASP,1994)定義(d236。jī)所導(dǎo)致的軀體痛和內(nèi)臟痛,第四頁，共三十三頁。ng)。ng)和神經(jīng)病理性疼痛(t233。ng)的發(fā)生機制和臨床癥狀，主要有兩種：傷害感受性疼痛(t233。ng)的病理生理學(xué)分類根據(jù)疼痛(t233。ng),With regard to the
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