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lerotic lesions unless they are exposed to arterial pressures and flow over extended periods of time. The risk factors for atherosclerosis include environmental and genetic factors. There are multiple theories of causation, including intimal trauma, an autoimmune response,and infection. Whatever the underlying pathogenesis, the key point to remember is that atherosclerosis is a systemic disease, affecting arteries in all vascular beds.,第四頁,共五十一頁。guǎn)成形術(shù)根本概念,Risk Factor for Atherosclerosis Genetic predisposition Smoking Diet Diabetes Chronic renal failure Hypertension Homocysteinuria Advanced age Hyperlipidemia Obesity Elevated lipoprotein (a) Atheromatous plaque. Eccentric atheroma,第五頁,共五十一頁。guǎn)成形術(shù)根本概念,第六頁,共五十一頁。guǎn)成形術(shù)根本概念,Angiographic appearance of concentric stenosis of the left common iliac artery,Angiographic appearance of bulky, eccentric plaque in the SFA,第七頁,共五十一頁。guǎn)成形術(shù)根本概念,Hypertrophied collateral arteries around a short chronic occlusion of the distal superficial femoral artery (SFA),. DSA showing an abrupt cutoff of flow with a filling defect (arrow) consistent with thrombus. There is a paucity of collateral vessels and lack of reconstitution of distal vessels.,第八頁,共五十一頁。guǎn)成形術(shù)根本概念,Intimal hyperplasia is not a true disease or disorder,but a biologic response to injury to the vessel wall. Causes of Intimal Hyperplasia Cause Examples Injury Surgical anastomosis, clamps, angioplasty denudation of intima by any device Foreign body Stents, suture material, catheters Abnormal flow Arterialization of veins, turbulence,第九頁,共五十一頁。s arteritis) Other factors,irregular beaded appearance (arrow) and location of the abnormality in the distal main renal artery,DSA arch aortogram showing occlusion of the left CCA (arrow) at the origin, long stenosis of the right CCA (arrowhead), and stenosis of the right subclavian artery origin,Takayasu39。,第一節(jié) 血管(xu232。sh249。,第十一頁,共五十一頁。