【正文】
酵罐的工作要求 作為反應釜,要求清潔衛(wèi)生、反應過程能保持恒定的溫度,以利于發(fā)酵菌很好地進行發(fā)酵。 發(fā)酵罐的優(yōu)點在于,它能進行嚴格的滅菌,通入空氣,提供 良好的發(fā)酵環(huán)境,能實施攪拌、震蕩等促進微生物生長的措施;能對溫度、壓力、空氣流量實行自動控制,能通過各種生物傳感器了解發(fā)酵罐內(nèi)的菌體濃度、營養(yǎng)成份等,并用電腦隨時調(diào)節(jié)發(fā)酵進程。罐體采用SUS304 或 316L 進口不銹鋼,罐內(nèi)配有自動噴淋清洗機頭,確保生產(chǎn)過程符合 GMP 要求。 發(fā)酵罐是一種對物料進行機械攪拌與發(fā)酵的設備。 For the uniform reaction, now is widely used in pharmaceutical, monosodium glutamate, enzyme system and food industries. Its main ponents include the reactor body, mixing equipment, heat transfer equipment and seal device. Also add other accessories needed, such as assembly and welding manhole, hand hole and all over (in pieces for ease of maintenance and feeding, nesting), install thermometers, pressure gauges, mirrors, safety relief device (for operation effectively monitor and control the material temperature, pressure) and so on. Mixing device is a gear, shaft and agitator stirring position, its role is to participate in a variety of materials, reaction mixed evenly, so that good contact material to accelerate the chemical reaction. Mixing devices can be divided into nondiving type (only driven machines and gear and transmission system disclosed in the liquid outside and dive type (from the driving machine to sneak into a liquid blender all) types. Heat transfer device is set in the interior of reactor body coil or external tank set up in the jacket, its role is to control the materials needed in the reaction temperature range. The design of the fermentation tank volume is 63 cubic meters,and this is a large tank design with coil heat transfer and three mixings. Key words: mixing tank; mixer; kettle body; heat transfer equipment; seal device; manhole.武漢工程大學 本科畢業(yè)(設計)論文 III 目 錄 摘 要 ............................................................ I Abstract .......................................................... II 前 言 ............................................................ I 概 論 ........................................................... II 發(fā)酵罐的特點 ................................................ II 發(fā)酵罐的工作要求 ............................................ II 發(fā)酵罐的設計依據(jù) ............................................ II 發(fā)酵罐的設計要求 ............................................ II 發(fā)酵罐的設計步驟 ............................................ II 設計內(nèi)容 ................................................... III 第一章 設計參數(shù)的選擇 ............................................. 1 、課程設計題目 ............................................... 1 、原始數(shù)據(jù) ................................................... 1 、已知條件 ................................................... 1 、設計壓力 ................................................... 3 、設計溫度 ................................................... 3 、材料的選擇 ................................................. 3 、基本的選型 ................................................. 3 第二章 容器 的結(jié)構(gòu)設計 ............................................. 4 、圓筒的設計 ................................................. 4 、圓筒的高和直徑 ........................................ 4 、圓筒的厚度 ............................................ 4 、封頭壁厚 ................................................... 5 、所裝料液高度 ............................................... 6 厚度裕量 ..................................................... 6 、軸的設計及校驗 ............................................. 6 、傳動軸長度 ................................................. 6 、軸徑 ....................................................... 6 武漢工程大學 本科畢業(yè)(設計)論文 IV 、臨界轉(zhuǎn)速 ................................................... 7 、有效質(zhì)量的計算 ....................................... 12 、一階臨界轉(zhuǎn)速的計算 ................................... 13 、按強度計算攪拌軸的軸徑 .................................... 14 、軸向的彎矩的計算: ........................................ 17 徑向位移驗算軸徑 ............................................ 18 第三章 主要部件的選擇 ............................................ 21 、減速機 .................................................... 21 、聯(lián)軸器 .................................................... 21 、密封 ...................................................... 21 、底軸承 .................................................... 22 、對支承的改進 .............................................. 22 第四章 傳熱計算 .................................................. 24 、傳熱面積 .................................................. 24 、蛇管總體長度 .............................................. 24 、蛇管組及每組長度 .......................................... 24 、每級蛇管排列圈數(shù) .......................................... 24 、傳熱面積的校驗 ............................................ 25 、冷卻水耗量 ........................................... 25 、傳熱面積校核 ......................................... 25 第五章 開孔補強及校核 ............................................ 27 、人孔補強 .................................................. 27 出料口接管補強 .............................................. 29 進氣口接管補強 .............................................. 31 、水壓試驗應力校核 .......................................... 33 、聯(lián)軸器的校核 .............................................. 33 、裙座的校核見裙座的設計 .................................... 33 第六章 裙座的設計 ................................................ 34 、基本性質(zhì) .................................................. 34 武漢工程大學 本科畢業(yè)(設計)論文 V 、裙座型式 .................................................. 34 、裙座與罐體連接型式 ........................................ 34 、排氣孔 .................................................... 35 、引出孔 .................................................... 35 、檢查孔 .................................................... 36 、裙座的設計和核算 .......................................... 37 第七章 改進方案 .................................................. 45 、改進一 : 增加穩(wěn)定器 ........................................ 45 、改進二 : 安裝氣體分布器 .................................... 46 、改進三 : 加設收集器 ........................................ 46 、改進四 : 替換蛇管 .......................................... 46 第八章 攪拌罐