【正文】
Y Population right。112(6):15349 ? MEDLINE Disa JJ. Polvora VP. Pusic AL. Singh B. Cordeiro PG. Dextranrelated plications in head and neck microsurgery: do the benefits outweigh the risks? A prospective randomized analysis. [Clinical Trial. Journal Article. Randomized Controlled Trial] Plastic amp。 Strategy ? Databases: PubMed, MEDLINE amp。 ?基於其可怕併發(fā)癥 , 使用之必要性令人懷疑 , 值得重新評(píng)估 。 ?Dextran 是常用的其中一種 , 卻又有嚴(yán)重併發(fā)癥的可能 , 如過(guò)敏性休克、急性腎衰竭、急性呼吸窘迫癥候群等 。將實(shí)證醫(yī)學(xué)納入臨床操作 以 Dextran之使用為例 徐圭璋 高雄榮民總醫(yī)院 “Leaks” between research amp。 practice Aware Accept Target Doable Recall Agree Done Valid Research x x x x x x = Prof. Paul Glasziou, EBM Centre, U. of Oxford, UK 實(shí)證醫(yī)學(xué)實(shí)作案例 ?顯微外科醫(yī)師為避免所接合的微小血管在術(shù)後阻塞 , 常用許多抗血栓劑 。 ?本科幾乎為常規(guī)使用 。 實(shí)證醫(yī)學(xué)五步驟 ?提出問(wèn)題 (Question formulation) ?搜尋證據(jù) (Evidence search) ?嚴(yán)格判讀 (Critical appraisal) ?恰當(dāng)運(yùn)用 (Evidence application) ?評(píng)估結(jié)果 (Oute evaluation) 實(shí)證醫(yī)學(xué)五步驟 ?提出問(wèn)題 (Question formulation) ?搜尋證據(jù) (Evidence search) ?嚴(yán)格判讀 (Critical appraisal) ?恰當(dāng)運(yùn)用 (Evidence application) ?評(píng)估結(jié)果 (Oute evaluation) Clinical Question (PICO) ? In patients with head and neck cancer, does use of dextran improve free flap survival rate? – P (population): Pts with head neck cancer