藥學(xué)畢業(yè)論文hplc法測(cè)定氧氟沙星滴眼液中氧氟沙星含量-展示頁(yè)
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【正文】 學(xué) 號(hào)： 專 業(yè)： 藥 學(xué) 指導(dǎo)老師： 職 稱： 執(zhí)業(yè)藥師 實(shí)習(xí)單位： 安徽中醫(yī)藥大學(xué)藥學(xué)院201X年6月安徽中醫(yī)藥大學(xué)藥學(xué)院本科畢業(yè)生畢業(yè)論文（設(shè)計(jì)）承諾書本人按照畢業(yè)論文（設(shè)計(jì)）進(jìn)度計(jì)劃積極開展實(shí)驗(yàn)、實(shí)踐研究活動(dòng)，實(shí)事求是地做好實(shí)驗(yàn)、實(shí)踐記錄，所呈交的畢業(yè)論文（設(shè)計(jì)）是我個(gè)人在導(dǎo)師指導(dǎo)下進(jìn)行的研究工作及取得的研究成果。據(jù)我所知，除文中特別加以標(biāo)注引用參考文獻(xiàn)資料外，論文（設(shè)計(jì)）中所有數(shù)據(jù)均為自己研究成果，不包含其他人已經(jīng)發(fā)表或撰寫過(guò)的研究成果。畢業(yè)論文（設(shè)計(jì)）作者簽名： 畢業(yè)論文（設(shè)計(jì)）指導(dǎo)教師簽名： 日期： 目 錄中文摘要...............................................1英文摘要...............................................21實(shí)驗(yàn)材料..............................................3................................................3................................................3................................................42方法與結(jié)果............................................4............................................4..........................................4......................................4......................................4......................................分離度、拖尾因子........................4........................................5........................................5....................................6..........................................7....................................7..........................................8......................................8.......................................93討論與結(jié)論...........................................10.....................................10 pH的影響..........................................10...........................................10.......................................10...............................................11參考文獻(xiàn)..............................................12致謝..................................................13綜述..................................................14中文摘要 目的：建立氧氟沙星滴眼液中氧氟沙星含量的高效液相色譜測(cè)定方法。 結(jié)果：~，線性回歸方程為Y=502505X+(r=)；%，相對(duì)標(biāo)準(zhǔn)偏差（RSD）%（n=9）。 關(guān)鍵詞：氧氟沙星；HPLC；含量測(cè)定；方法學(xué)研究ABSTRACTObjective: To establish a HPLC method for the content determination of Ofloxacin in Ofloxacin eye drops.Methods:HPLC method, the chromatographic column was Hypersil C18(5μm，250）。the flow rate was ,while the column temperature was setting at 30℃,and detecting wavelength at 293nm.Results:The linear ranges was ~, the recovery was %, RSD was %(n=9) . Conclusion: The method was sensitive, accurate and high specific for content determination of Ofloxacin in Ofloxacin eye drops. Key words：Ofloxacin； HPLC；Determination of content；Methodological resear
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