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Endodontic Journal. On the causes of persistent apical periodontitis: a review 與口腔的關系 Further, there are extraradicular factors – located within the inflamed periapical tissue – that can interfere with posttreatment healing of apical periodontitis. The causes ……h(huán)ave not been well characterized, but there are six biological factors that lead to asymptomatic radiolucencies persisting after root canal treatment. ? (i) intraradicular infection persisting in the plex apical root canal system。 ? 形成生物被膜的黏附細菌群也可以釋放出浮游細菌,是潛在的持續(xù)感染因素。細菌生物膜 內容適合醫(yī)學院 35年級學生使用 “In a paper in Science in 1999, we said 65 percent of all diseases in the developed world are biofilms,” Costerton said. “Now the NIH says 80 percent. ” Biofilms — matrixenclosed microbial accretions/逐漸生長 /增加 that adhere to biological or nonbiological surfaces. on a contact lens on a spider 細菌生物膜廣泛存在于自然環(huán)境中 細菌生物膜廣泛存在于自然環(huán)境中 ? Biofilm formation appears early in the fossil record ( billion years ago) and is mon