高血壓心血管事件的臨床研究(ppt51)英文-經(jīng)營(yíng)管理-展示頁(yè)
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【正文】 atment worse than placebo He J, et al. Am Heart J. 1999。138:211219. Copyright 1999, Mosby Inc. 來(lái)自 020406080100Ageadjusted annual CVD event rate per 1000 Wilking SV et al. JAMA. 1988。 287:10031010. Copyright 2020, American Medical Association. 來(lái)自 Mortality According to Blood Pressure in Men Age 50 to 69 0501001502002501581671481571381471281379812798 10 293 9788 9283 8768 82Society of Actuaries. Blood Pressure Study, 1939. Ratio (%) of actual to expected mortality Systolic blood pressure (mmHg) 來(lái)自 0102030405060 1 2 0 120139140159160179180+0102030405060 7 5 7584859495104105+Ageadjusted annual incidence of CHD per 1000 Based on 30 year followup of Framingham Heart Study subjects free of coronary heart disease (CHD) at baseline Systolic blood pressure (mmHg) Blood Pressure and Risk for Coronary Heart Disease in Men Diastolic blood pressure (mmHg) Age 6594 Age 3564 Age 6594 Age 3564 Framingham Heart Study, 30year Followup. NHLBI, 1987. 來(lái)自 01234Relative risk of CHD mortality He J, et at. Am Heart J. 1999。The Relationship of Systolic and Diastolic Blood Pressure to Cardiovascular Disease Risk: Observational Data 來(lái)自 020406080Prevalence of Hypertension in the US Percent hypertensive 1829 Based on NHANES III (phase 1 and 2) Hypertension defined as blood pressure ?140/90 mmHg or treatment 3039 4049 5059 6069 7079 80+ Age 3 % 9 % 18 % 38 % 51 % 66 % 72 % JNCVI. Arch Intern Med. 1997。157:24132446. 來(lái)自 0204060801000 2 4 6 8 10 12 14 16 18 20Risk of hypertension (%) Residual lifetime risk of developing hypertension among people with blood pressure 140/90 mmHg Years Lifetime Risk of Developing Hypertension Beginning at Age 65 Men Women Vasan RS, et al. JAMA. 2020。138:211219. Copyright 1999, Mosby Inc. 112 71 Risk of CHD Death According to SBP and DBP in MRFIT 1 2 3 4 5 6 7 8 9 10 Decile 112 71 118 76 121 79 125 81 129 84 132 86 137 89 142 92 151 98 (lowest 10%) (highest 10%) SBP (mmHg) DBP (mmHg) Systolic blood pressure (SBP) Diastolic blood pressure (DBP) CHD=coronary heart disease 來(lái)自 0123456789Relative risk of stroke death 112 71 Risk of Stroke Death According to SBP and DBP in MRFIT 1 2 3 4 5 6 7 8 9 10 Decile 112 71 118 76 121 79 125 81 129 84 132 86 137 89 142 92 151 98 (lowest 10%) (highest 10%) SBP (mmHg) DBP (mmHg) Systolic blood pressure (SBP) Diastolic blood pressure (DBP) He J, et at. Am Heart J. 1999。260:34513455. Men Women Isolated Systolic Hypertension and CVD Risk in Framingham ISH BP ?160/95 mmHg BP 140/95 mmHg 82 43 33 18 CVD=cardiovascular disease ISH=isolated systolic hypertension P for difference between both men and women with ISH and blood pressure (BP) 140/95 mmHg 來(lái)自 The Relationship of Hypertension Treatment to CVD Risk Reduction: Introduction 來(lái)自 024681012Incidence of cardiovascular disease 120 Hypertension Treatment Effect Mirrors Observational Data 140 160 180
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