【正文】
共三十八頁(yè)。 location of lesions,Tortuosity,Thrombus,Bifurcation,Total Occlusion,Diffuse,Left Main,Dominance,SYNTAX Score,Calcification,EuroInterv 2005。,SYNTAX CABG/PCI Registries,SYNTAX appendix: NEJM, 2009,Reasons for CABG,Complex anatomy 70.9% Untreatable chronic 22.0% total occlusion Unable to take 0.9% antiplatelet medications Patient refused PCI 0.5% Other 5.7%,Reasons for PCI,Comorbidity 70.7% No graft material 9.1% Patient refused CABG 5.6% Small or poor quality 1.5% of distal vessel Other 13.1%,n=644,n=192,第十六頁(yè),共三十八頁(yè)。 interventionalist),Amenable for only one treatment approach,Amenable for both treatment options,Stratification: LM and Diabetes,LM 33.7%,3VD 66.3%,LM 34.6%,3VD 65.4%,23 US Sites,62 EU Sites,+,SYNTAX Trial Design,*TAXUS Express,第十四頁(yè),共三十八頁(yè)。,SYNTAX Inclusion Criteria,3vessel disease and/or left main disease Total occlusion without time limitation Previous stroke 1 month Renal and respiratory insufficiency Decreased pump function Myocardial ischemia (unstablesilentstable) Patients with comorbidity,Real world patient population,第十三頁(yè),共三十八頁(yè)。,CABG vs DrugEluting Stents in Multivessel Coronary Disease A MetaAnalysis on 24,268 Patients,Benedetto et al: EJCTS 6958, 2009,Favors DESPCI,Favors CABG,0.01 0.1 1 10 100,HR and 95% CI,Study name Park Hannan Briguori Yang JH Lee Yang ZK Javaid Varani Tarantini,第十一頁(yè),共三十八頁(yè)。,Increased Likelihood of Restenosis Lesion/Patient Subsets,Small vessels Bifurcations Ostial CTO Bare metal ISR SVG AMI (thrombus) Diabetes mellitus,第九頁(yè),共三十八頁(yè)。,Extension of Survival with CABG vs Medical Therapy After 10 Years,CP120301814,Extension of survival (mo),Yusuf S et al: Lancet 344:563, 1994,Overall,Vessel disease 1/2 vessels 3 vessels Left main,LV functio