diseaseofhematopoieticandlymphoidsystem-文庫(kù)吧資料
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【正文】 ing Hodgkin’s tissue: lacunar cells often numerous (often mediastinal presentation) 2. Mixed cellularity (25%) Plasma cells and eosinophils present in addition to RS cells and lymphocytes. Hodgkin disease, mixed cellularity type. 3. Lytnphocyte Depleted (15%) Very numerous RS and mononuclear Hodgkin’s cells, few lymphocytes and some diffuse fibrosis. 4. Lymphocyte predominant (5%) Very numerous lymphocytes Scanty RS cell Divited into 2 types: 1) . Nodular type 2), Diffuse type Transtion from better to worse prognosis type occurs 4→ 2→3 but nodular sclerosing usually remains true to Complications The immunity function is lower (reduce) The patient easily suffer from infection of virous and fungus. The Non Hodgkin lymphomas The non Hodgkin lymphoma are solid tumours arising in the peripheral lymphoid tissue particularly of lymphnodes but also of the extranodal sites such as the oro pharynx, the gut, skin and other sites. Grossly: The same as Hodgkin’s diseases but the mass is more soft and a few necrosis. The normal architecture of lymph node have been. Destroyed partly or entirely. Very numerous monotonous neoplastic cell flood in lymph node. The neoplastic cell may be infiltrate to the capsule of node. Classification 1. Rappaport classification The traditional classification is purely morphological criteria. The subset: ① nodular type ② diffuse type Then according to differentiated degree of tumor cell again divided into several type: (well, poorly, nodifferentiated) 2. Lukes Collins classification The NHL are classificed into T cell, B cell and null cell, histiocytic categories by using immunologist and catechetical markers as adjuncts to morphology. B細(xì)胞型淋巴瘤 小淋巴細(xì)胞 （ B） 型 漿細(xì)胞樣淋巴細(xì)胞型 濾泡中心細(xì)胞型 小核型濾泡中心細(xì)胞型 大核型濾泡中心細(xì)胞型 小無(wú)核型濾泡中心細(xì)胞型 Burkitt淋巴瘤 非 Burkitt淋巴瘤 大無(wú)核裂濾泡中心細(xì)胞型 免疫母細(xì)胞型淋巴瘤 （ B T細(xì)胞型淋巴瘤 小淋巴細(xì)胞 （ T） 型 曲折核淋巴細(xì)胞型 腦回狀核淋巴細(xì)胞型 （ 蕈樣霉菌病 ， Sezary綜合征 ） 免疫母細(xì)胞型淋巴瘤 （ T） 組織細(xì)胞型淋巴型 未定型淋巴瘤 Classification of The Non Hodgkin lymphomas 非霍奇金淋巴瘤的 KIEL分類 B細(xì)胞性 T細(xì)胞性 低度惡性 淋巴細(xì)胞性 慢性淋巴細(xì)胞白血病 前淋巴細(xì)胞白血病 毛細(xì)胞白血病 淋巴漿細(xì)胞性 /淋巴漿細(xì)胞樣 漿細(xì)胞性 中心母細(xì)胞 /中心細(xì)胞性 濾泡型 177。Disease of Hematopoietic and Lymphoid System Tian Dong ping （田東萍） Department of Pathology, Shantou University Medical College 2022／５ １２ A. Hemopoietic Organs ? Bone Marrow, ? Liver, Spleen ? Lymph node ? Tonsil, etc Section 1 Introduction 量的改變 質(zhì)的改變 Section two Leukopenia Neutropenia(白細(xì)胞減少癥 ) Agranulocytosis(粒細(xì)胞缺乏癥 ) 1000/uL 200300/uL Section two Leukopenia Etiology and Pathogenesis Inadequate granulopoiesis Accelerated removal or destructi
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