哈爾濱醫(yī)科大學(xué)神經(jīng)病學(xué)中樞神經(jīng)系統(tǒng)脫髓鞘疾病-文庫(kù)吧資料
2025-06-01 05:40本頁(yè)面
【正文】 診斷 發(fā)作次數(shù) 臨床病灶數(shù) 亞臨床證據(jù) CSF OB/IgG 臨床確診（ CDMS） 2 2 2 1 及 1 實(shí)驗(yàn)室支持確診(LSDMS） 2 1 1 1 2 1 或 1 及 1 + + + 臨床可能 (CPMS) 2 1 1 1 2 1 1 + 實(shí)驗(yàn)室支持可能(LSPMS） 2 兩次發(fā)作均累及CNS不同部位，間隔至少一個(gè)月，每次持續(xù) 24小時(shí)。 CSF OB/IgG。 ③ one attack, one lesion and other subclinical evidence。 3. Clinical probable MS (CPMS): ① two attacks, one lesion 。 ② One attack, two lesions and CSF OB/IgG 。 ② two attacks, one lesion and one subclinical evidence。 ③ atrophy symptom. Abnormal MRI scans are found in 96% with a definite diagnosis of MS 70% with a diagnosis of probable MS 30 50% with a diagnosis of possible MS MRI Criteria for diagnosing MS At least 3 Lesions and two of the following: 1 Lesions abutting the Lateral Ventricles 2 Lesions with diameters greater than 5mm 3 Lesions present in the Posterior Fossa Source (Offenbacher H, Fazekas F, Schmidt R et al. Assessment Of MRI Criteria For A Diagnosis Of MS*Neurology 1993。 ③ somatosensory evoked potentials(SEP). 3) MRI : ① preiventricular plaques。 ④ CSFAlb/serumAlb(probability of MS) 2) Evoked potentials: 50%90% abnormal. ① visual evoked potentials(VEP)。 oligoclonal bands(OB) (95%)。 ⑧ Other clinical feature. 6. Laboratory and assistant Tests 1) CSF Test ① Number of MNC15? 106/L。 ⑥ Impairment of PNS。 (internuclear ophthalmoplegia, PPRF one and a half syndrome) “一個(gè)半綜合征” 垂直眼震 ④ Sensation disorder: Romberg’s sign, (1/2) Lhermitte’s sign。 ② The visual loss in one or both eyes。 ③ Nystagmus。 肉眼觀： CNS內(nèi)脫髓鞘斑塊 5. Clinical Manifestations 1) Prodrome: The symptoms evolved more slowly, over seve
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