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– 329 :673 82. Thirtyday mortality and stroke in the four treatment groups Mortality (%) Stroke (%) SK + IV heparin SK + SC heparin tPA + SK + IV heparin Accelerated tPA Comparison with accelerated tPA* P *P= for accelerated tPA pared with both SK strategies GUSTOI: Global Utilization of Streptokinase and tPA for Occluded coronary arteries I SUMMARY ? Although there was an excess of hemorrhagic stroke with tPA plus heparin, pared with the other regimens, the bined 30day endpoint of death or disabling stroke was significantly lower with accelerated tPA ? An aggressive thrombolytic strategy usin