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【正文】 infarction Reference The GUSTO Investigators. An international randomized trial paring four thrombolytic strategies for acute myocardial infarction. N Engl J Med 1993。329:67382. ： ； :； ： GUSTOI: Global Utilization of Streptokinase and tPA for Occluded coronary arteries I TRIAL DESIGN Design: Randomized, parallel group Patients: 41,021 patients with AMI, 6h after onset of symptoms Follow up and endpoint: Primary endpoint death at 30 days Treatment: Four thrombolytic strategies pared: ? Streptokinase (SK) ( million U over 60 min) and SC heparin (12,500 U twice daily) ? SK ( million U over 60 min) and IV heparin (bolus 5000
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