【正文】
Strains Controls ? Free of charge up to the number of mutant mice ordered (no specific age or gender requirements) ? $ per mouse in excess of the number of mutant mice ordered or for specific age or gender requirements 生物統(tǒng)計(jì) Analysis of Variance I 小鼠競價(jià)! Jakson Lab ? ? Pricing is based on the strain of mouse ordered (., inbred, transgenic, spontaneous mutant, etc.), the size of the colony, age of the mouse, husbandry practices, and other factors. ? Pricing for Retired Breeders ? Pricing for Pregnant Females 生物統(tǒng)計(jì) Analysis of Variance I 小鼠競價(jià)! Jakson Lab ? 到底多少錢? ? 雌雄哪個(gè)貴? ? 例子: available to Asia – only few strains – 6weeks US$$ (+US$ for international for Littermate) ? USA, Canada, Mexico – Pregnant female: $ $ ? 獲獎?wù)撸禾镬o芳和陳戈靈 生物統(tǒng)計(jì) Analysis of Variance I 均方及均方的期望 EEEAAA dfSSMSdfSSMS ?? , 新的統(tǒng)計(jì)量 其期望: ????2221)()(iandfMSEMSEiAAE??ai是處理的效應(yīng)值 當(dāng) H0成立時(shí), ai = 0: 22 0)( ?? ???AMSEEAMSMSF ?檢驗(yàn)統(tǒng)計(jì)量:1)( )()( 22??? ??EAMSEMSEFE當(dāng) H0不成立時(shí),至少一個(gè) ai?0: 1)()( 2 ??? FEMSEA ?。 生物統(tǒng)計(jì) Analysis of Variance I 小鼠競價(jià)! Jakson Lab ? Specific age in days: Price by age in weeks + $ per mouse. ? Mice 17 days of age or younger: List price + $ per mouse + lactating female price. ? Lactating female: $ per mouse. ? Littermates: List price + $ per mouse (weaning age only). ? Identification by vaginal plug, 0 to 10 days (pregnancy not guaranteed) $ ? Identification by palpation, 11 to 15 days (pregnancy guaranteed) $ ? Free of charge up to the number of mutant mice ordered (no specific age or gender requirements) ? $ per mouse in excess of the number of mutant mice ordered or for specific age or gender requirements ? Littermates: List price + $ per mouse (weaning age only) ? Pricing for JAX174。????生物統(tǒng)計(jì) Analysis of Variance I 多重比較 Duncan’s 多重極差檢驗(yàn) 一共有 k個(gè)平均數(shù)-即 k個(gè)處理, 按大小排隊(duì) ,比較任意兩個(gè),確定各平均數(shù)對子間包含的平均數(shù)個(gè)數(shù)(包括自身);先計(jì)算出 一套 最小顯著極差,然后將兩平均數(shù)的差與之相比,大于則顯著! 2個(gè)平均數(shù) 4個(gè)平均數(shù) 3個(gè)平均數(shù) ? 4321????XXXX生物統(tǒng)計(jì) Analysis of Variance I 多重比較 Duncan’s 多重極差檢驗(yàn) ? 將小鼠的脾臟重量的平均數(shù)按由大到小順序排列 ? 確定各平均數(shù)對子間包含的平均數(shù)個(gè)數(shù)(包括自身) ? 計(jì)算一套最小顯著極差值 ???????????jiEEij nnMSdfrSSRL S R1121),(?Least significant range standardized significant range ?ji nn ?0HL SRXX ijji則否定如果 ??假設(shè): H0: ?i= ?j; HA: ?i? ?j 生物統(tǒng)計(jì) Analysis of Variance I 多重比較 Duncan’s 多重極差檢驗(yàn) range 2 3 4 3 8 3 7 6 *7181216 9 7 )28,2()(12?????????????? SSRL S R ????????????jiEEij nnMSdfrSSRL S R1121),(?8 6 4 7 6 *)(12 ????L S R生物統(tǒng)計(jì) Analysis of Variance I 多重比較 Duncan’s 多重極差檢驗(yàn) ? 結(jié)果不一樣! mean pairs “MSE” range 2 ** 3 ** 4 ** 2 3 ** 2 21 XX ?31 XX ?41 XX ?32 XX ?42 XX ?4