【正文】 55: 498–510 ? Mechanism of DAGPKC activation Email: ?Physiological effects and cellular mechanisms of DAGPKC activation induced hyperglycemia Pharmacological Research 20xx。 Research 20xx。 Research 20xx。 Research 20xx。 55: 487–497 Email: PKC amp。5:43143) ?aPKC? is highly expressed in human non–small cell lung carcinoma (NSCLC) lines, whereas the closely related PKC isozyme, aPKC?, is undetectable in these cells. (J Biol Chem 20xx。36:11416.) ?PKC activity is higher in actively proliferating colonic epithelial cells than in their quiescent counterparts. (J Biol Chem 20xx。12: 53365345 Email: ?Schematics illustrating the factors involved in intracellular signaling pathways downstream of PKC? Clin Cancer Res 20xx。12: 53365345 Email: ?Schematics illustrating the factors involved in intracellular signaling pathways downstream of PKC? Clin Cancer Res 20xx。 Cancer PKC Involved in Pathophysiologic Disorders Email: ? Schematic of placement of PKC isoforms in intracellular signaling pathways Clin Cancer Res 20xx。 55: 523–536 Email: ?Proposed mechanism for nPKC?mediated regulation of mitochondrial function leading to IR injury Pharmacological Research 20xx。 NRM: nucleus raphe magnus. Email: PKC amp。 PAG: periaqueductal gray。 55: 578–589 Email: ? Inhibition of nociception by brain (intracerebroventricular) administration of PKC inhibitors Pharmacological Research 20xx。 MH:mechanical hyperalgesia。 55: 578–589 Neurokinin receptor (NK1), metabotrophic glutamate receptors (mGluR) that bind excitatory amino acids (EAA), and receptors for calcitonin generelated peptide (CGRP). Email: ? Inhibition of nociception by peripheral administration of PKC inhibitors Pharmacological Research 20xx。 55: 578–589 Voltage gated calcium channels (VDCC)。 55: 578–589 Bradykinin (BK), endothelin1 (ET), prostaglandins (PGE2), cytokines (tumor necrosis factor, TNF), ATP, trypsin, galanin, and insulin。 55: 560–569 Email: PKC amp。 6: 136–49.) Email: ?CNS diseaserelated changes in PKC signal transduction in human brain Pharmacological Research 20xx。 Basal ganglia diseases PKC Involved in Pathophysiologic Disorders Email: ?Basal ganglia diseases ?PKC levels were reduced in HD and in PD patients with dementia but not in those with preserved cognitive functions. (Adv Neurol 1993。 28: 5160 早老素 Email: ?Overview of the pathways in AD and learning and memory that involve PKC TRENDS in Pharmacological Sciences 20xx。 28: 5160 Email: ?Effects of PKCmediated protein phosphorylation in postsynaptic partment TRENDS in Pharmacological Sciences 20xx。 67: 317–23) ?In peripheral Tcells from early AD patients, A? increase nPKC? expression, while in severe AD patients A? induces nPKC? and aPKC? expression. (Neurobiol Aging 20xx) Email: ? PKC activates ?secretase indirectly or directly through ERK1/2 TRENDS in Pharmacological Sciences 20xx。 Cerebral Hypoxic Preconditioning PKC Involved in Pathophysiologic Disorders Email: ?Hypoxic Preconditioning When exposed to s