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Discussion 第四十頁(yè),共四十頁(yè)。 ? Involved vessels may appear tortuous, rigid or irregularly widening and link to pulmonary arteries or pulmonary veins. ? In this study, the GGNvessel relationships were categorized into four types . Statistical analysis indicated that when the relationship was type III or IV, especially type IV, it was highly likely that GGNs were malignant invasive adenocarcinoma, with MIA more than IAC. ? In contrast, the majority of benign and preinvasive cases was seen in type I or type II GGNvessel relationships. 第三十七頁(yè),共四十頁(yè)。 ? As a result , involved vessels might appear distorted, rigid or concentrated towards the lesion. ? Thus, it is reasonable to postulate假設(shè) that the vascular convergence sign monly seen in SPNs. ? Actually, the type IV GGNvessel relationship resemblesVCS to some degree. ? The invasive adenocarcinoma group is posed of two subgroups, MIA and IAC. Subgroup analysis showed MIA and IAC had different patterns of GGNvessel relationships. 第三十四頁(yè),共四十頁(yè)。 ? This demands further investigation of this particular abnormal imaging finding to minimise misdiagnosis. In the management of GGNs in our patients, clinical guidelines from the Fleischner Society and National Comprehensive Cancer Network (NCCN) were referenced . ? Each individual case was discussed by a multidisciplinary team, including diagnostic radiologists, thoracic surgeons and pathologists, to generate consequent management strategies. ? All patients received adequate followup observation with/without supportive or antiinflammatory treatment, which explained the fact that four GGNs disappeared prior to the next scheduled CT examination. 第三十頁(yè),共四十頁(yè)。 Discussion ? Solitary pulmonary nodules (SPNs) are mon findings in ? CT examinations and can be divided into two groups based ? on density variation: solid nodules and GGNs. ? In 2024, the International Association for the Study of Lung Cancer, the American Thoracic Society and the European Respiratory Society proposed a new classification for lung adenocarcinomas. ? In the new classification system, the term bronchioloalveolar carcinoma (BAC) is no longer used. The former BAC concept applicable to multiple categories in the new classification system, such as AIS, MIA and the mucinous subtype of adenocarcinoma. Both AIS and AAH lesions are classified as preinvasive adenocarcinoma under the new classification system ? 第二十七頁(yè),共四十頁(yè)。 MIA could present four types, with type II as the major type ( %). The bination of type II and IV prised about 80 % of the MIA subgroup。 mm, respectively. ? No significant differences existed between the preinvasive group and the benign group (t = ?,p=). ? However, there were significant differences between benign and preinvasive groups and the invasive adenocarcinoma group (t = ?,p=。 Statistical analysis ? SPSS for Windows, SPSS, Chicago, Ill ? Independent t test was used to pare different pathological groups (benign diseases, preinvasive diseases and invasive adenocarcinoma) of GGN. ? Correlations between pathological findings of GGNs and GGNvessel relationships were examined using Spearman’ s rank test. ? GGNvessel relationships between MIA and IAC diseases were pared using Pearson’ s chisquared test. ? When there was an expected value 1 or a pretest probability close to the test level, Fisher’ s