褐藻糖膠fucoidan對(duì)腫瘤細(xì)胞的抑制作用-wenkub.com
2026-01-06 02:01 本頁(yè)面
【正文】 ?活化之後的 NFκB 進(jìn)入細(xì)胞核中並引發(fā)特定基因轉(zhuǎn)錄及表現(xiàn)， 產(chǎn)生後續(xù)發(fā)炎反應(yīng)、調(diào)控細(xì)胞凋亡及進(jìn)一步導(dǎo)致腫瘤 之發(fā)生。 Caspases引發(fā)一連串蛋白質(zhì)酶解作用，傳遞死亡訊息給下游酵素，進(jìn)一步造成 DNA的片段化。 凋亡晚期 凋亡早期 圖、 磷脂絲氨酸 (PS)外翻 (Annexin VFITC/PI 雙染法 )分析 Fucoidan對(duì)於人類肝癌細(xì)胞株 Hep G2 誘導(dǎo)之細(xì)胞凋亡。 % % % % 在細(xì)胞週期中： G1時(shí)期就是細(xì)胞開始休息。87 fucose 1.「誘導(dǎo)癌細(xì)胞凋亡（ Apoptosis）」 2.「活化免疫作用」 3.「抑制血管新生作用」 ANTITUMOR?! （ A） （ B） 圖、 Fucoidan處理人類肝癌細(xì)胞之細(xì)胞型態(tài)變 化，箭頭處為細(xì)胞型態(tài)不完整。行政院農(nóng)業(yè)委員會(huì)水產(chǎn)試驗(yàn)所 黃培安 褐藻醣膠 (Fucoidan) 對(duì)於腫瘤細(xì)胞之抑制作用 What is Fucoidan？！ The polysaccharide was named as “fucoidin” when it was first isolated from marine brown algae by Kylin in 1913. but some also called it fucan, fucosan or sulfated fucan. Now it is named as “fucoidan” according to IUPAC rules. Fucoidans are sulfated polysaccharides extracted from marine brown seaweed. (Matou et al., 2022) Fucoidan is major posing of fucose, uronic acid, galactose, xylose and sulphated fucose. (Marais and Joseleau, 2022) The chemical positions of most fucoidans are plex. The structures of fucoidans from different brown algae vary from species to species. (Li et al., 2022) Fucoidan contains a substantial percentage of Lfucose and sulfate ester groups, and
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