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【正文】 first line treatment for moderate or severe depressionLifestylePhysical exercise is remended for management of mild depression, and has a moderate effect on symptoms. Exercise has also been found to be effective for (unipolar) major depression. It is equivalent to the use of medications or psychological therapies in most people. In the older people it does appear to decrease may be remended to people who are willing, motivated, and physically healthy enough to participate in an exercise program as treatment.There is a small amount of evidence that skipping a night39。s sleep may improve depressive symptoms, with the effects usually showing up within a day. This effect is usually temporary. Besides sleepiness, this method can cause a side effect of mania or hypomania.In observational studies smoking cessation has benefits in depression as large as or larger than those of medicationsRangeMajor depressive disorder affects approximately 253million people in 2013 (% of the global population).The percentage of people who are affected at one point in their life varies from 7% in Japan to 21% in most countries the number of people who have depression during their lives falls within an 8–18% range. In North America, the probability of having a major depressive episode within a yearlong period is 3–5% for males and 8–10% for depression to be about twice as mon in women as in men, although it is unclear why this is so, and whether factors unaccounted for are contributing to this. The relative increase in occurrence is related to pubertal development rather than chronological age, reaches adult ratios between the ages of 15 and 18, and appears associated with psychosocial more than hormonal factors. Depression is a major cause of disability worldwide.People are most likely to develop their first depressive episode between the ages of 30 and 40, and there is a second, smaller peak of incidence between ages 50 and risk of major depression is increased with neurological conditions such as stroke, Parkinson39。s disease, or multiple sclerosis, and during the first year after is also more mon after cardiovascular illnesses, and is related more to a poor oute than to a better conflict on the prevalence of depression in the elderly, but most data suggest there is a reduction in this age group. Depressive disorders are more mon to observe in urban than in rural population and the prevalence is in groups with stronger socioeconomic factors . homelessness.
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