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with nonresectable, locally advanced, nonmetastatic disease have a median survival of 6–11 months, and those with metastatic disease have a median survival of 2–6 months. Most patients develop disease recurrence within 2 years of resection, usually after a mean time of 9–12 months in the retroperitoneum (34–87%), the peritoneum(19–53%), the liver (38–73%), extraabdominal sites (8–29%). Liver metastases frequently develop earlier(at approximately 5–11 months postsurgery), indicating the presence of micrometastases at the time of surgery, whereas local recurrences tend to appear a little later (about 13 months postsurgery) . Should known for the Radiologists 腫瘤侵犯血管 ?不可切除 Limited Criteria: 血管周徑 1/2 + 血管長(zhǎng)徑 2 cm Other factors: operator’s skill and patient’s condition 腫瘤 TNM分期 ? 手術(shù)切除性判斷 2D + 3D more accuracy in determining the resectebility Artery differs from venous 高端 MRI ()的價(jià)值 補(bǔ)充 MDCT (特別疑難病例) 無(wú)輻射效應(yīng),可短期多次檢查 病人必須配合 技術(shù)要求高 圖象解釋較復(fù)雜 更依賴(lài)設(shè)備優(yōu)劣 經(jīng)驗(yàn)豐富的放射科醫(yī)生 MRI檢查方法 一、 SE序列: ① T1WI+ T2WI+DWI ② T1WI+FS 由于胰腺腺泡組織含較高的水樣蛋白成份,信號(hào) ↑,顯示胰腺輪廓十分清晰,與腫瘤的信號(hào)差異擴(kuò)大,該技術(shù)被普遍應(yīng)用。 二、 GRE 序列 : 動(dòng)態(tài)增強(qiáng): 動(dòng)脈期,胰腺期和門(mén)脈期 (axial and coronal scans for detection and MRA)。 ① Gd+ 1520 ml Vol, 10s hand injection ② time of images= delay time(10s)+injection time (10s)+half time of K space 三、 MRCP檢查 : 顯示 CBD及 PD。 CT 和 MRI 比較 胰腺癌首選 CT(主要雙期或三期增強(qiáng)掃描 ) 對(duì)疑難病例, MRI可補(bǔ)充 發(fā)現(xiàn)肝臟轉(zhuǎn)移灶, MRI敏感,尤其 T2WI 發(fā)現(xiàn)淋巴結(jié)轉(zhuǎn)移, CT敏感 腫瘤切除性判斷, CT較優(yōu) MRCP必須結(jié)合 T T2WI和增強(qiáng) GRE CT和 MRI互為補(bǔ)充 Acknowledgements Radiology General Surgery 殷允娟 碩士 靳大勇 教授 王冬青 博士 樓文輝 副教授 李 卉 博士 王單松 副教授 史 訊 碩士 陳偉中 碩士 姚秀忠 博士 饒圣祥 博士 Thanks for your attention wele to Zhongshan Hospital