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early intramuscular vaccination. 早期肌肉免疫可能受到母源抗體干擾 Pigs may be successfully vaccinated intranasally even at birth in the presence of maternal antibody, but the immunity may be relatively shortlived. 出生時的鼻腔接種可不受母源抗體干擾,但免疫力時間短 Very early (at birth) vaccination should be followed with a intranasal booster at 3 4 weeks of age, and an intramuscular booster at 7 to 9 weeks of age. 出生免疫后應(yīng)在 3- 4周齡時鼻腔接種和 7- 9周齡時 肌肉免疫進(jìn)行強化 When vaccinating at 34 weeks of age, a single IM booster at 7 to 9 weeks of age should be sufficient. 首次免疫在 3- 4周齡時, 7- 9周齡時肌肉免疫強化一次足夠 6 8 10 12 14 16 周 偽狂犬病免疫模型 A G E24222022161412108642REVSN1 . 0.9.8.7.6.5.4.3.2.10 . 00 1 感染母豬 感染仔豬 陽性 陰性 2 4 6 8 10 12 14 16 18 20 22 24 抗 體 水 平 周齡 偽狂犬病 gE (gI) ELISA gE (gI) A G E24222022161412108642REVSN1 . 0.9.8.7.6.5.4.3.2.10 . 00 1 感染母豬 感染仔豬 陽性 陰性 2 4 6 8 10 12 14 16 18 20 22 24 抗 體 水 平 什么時候感染? ? + 感染 gE (gI) A G E24222022161412108642REVSN1 . 0.9.8.7.6.5.4.3.2.10 . 00 1 感染母豬 感染仔豬 陽性 陰性 2 4 6 8 10 12 14 16 18 20 22 24 抗 體 水 平 周齡 什么時候打疫苗? 打疫苗 gE (gI) In the Face of an Outbreak 爆發(fā)時 An accurate diagnosis is essential. 必需進(jìn)行急性診斷 The most rapid onset of immunity is developed by intranasal vaccination. 鼻腔接種可最快產(chǎn)生現(xiàn)場免疫力 Animals of all ages can be vaccinated in this manner. 各年齡段豬都可以此法免疫 Intranasal vaccination can stimulate interferon and local immunity. 鼻腔接種可刺激干擾素和局部免疫產(chǎn)生 Vaccination can be repeated in 3 to 4 weeks if desired. 必要時 3- 4周后可重復(fù)免疫 Controlling/Eliminating Pseudorabies 控制 /消除偽狂犬病 Simple and Straightforward with Current Technology 現(xiàn)有技術(shù)簡單直接 Allin/Allout in nursery, growingfinishing. 保育豬,生長肥育豬全進(jìn)全出 Vaccinate with GI (GE) Gene Deleted Vaccine 基因缺失苗免疫 All in/All out plus vaccination should result in a readysupply of negative replacement females. 全進(jìn)全出結(jié)合免疫可為生產(chǎn)陰性后備豬打好基礎(chǔ) Replacement females will stay negative if sow herd is vaccinated 3 to 4 times per year. 如果母豬群進(jìn)行定期免疫,后備母豬可保持陰性 Vaccinate Sows every 3 or 4 months 母豬每隔 3 或 4 月免疫一次 Vaccinate Piglets intranasally at 3 weeks. 小豬 3 周齡時鼻腔免疫 Revaccinate Piglets IM at 79 weeks of age. 7- 9周齡時肌注免疫 Vaccinate New Stock 2X at Introduction. 新引入個體免疫 2 頭份 Residual infected animals can be removed by test and removal after 23, at most 4 years on the program 其余感染個體,通過 2- 4 年的計劃經(jīng)檢測和淘汰而清除