動物生理學(xué)5呼吸系統(tǒng)生理上-資料下載頁
2025-05-13 17:17本頁面
【正文】 ide is stored in three forms in blood, in physical solution, as bicarbonate, and in bination with protein, as carbamino pound. Although the dissolved O2 and CO2 are very small parts they are very important. Transport of O2 Hemoglobin is a conjugated protein consisting of a ferrous ironporphyrin pound (heme) joined to the protein globulin. Each Fe2+ molecule of Hb bines loosely and reversibly with one molecule of O2. Fully oxygenated hemoglobin carries ml O2/g of Hb. If the Fe2+ is oxidized to Fe3+, the pound is no longer able to transport O2 4 moles O2 /1mole Hb= 4* L / 64458g = ml/g ? Oxygen capacity (氧容量 ) normally 20 ml/100ml blood ? Oxygen content (氧含量 ) ? Oxygen saturation (氧飽和度 ) = content / capacity Oxygen dissociation (equilibrium) curve 氧解離曲線 oxygen dissociation curve The position of O2 equilibrium curve can change owing to other physiological factors. The major factors affecting O2 affinity are Pco2, pH, temperature and 2,3diphosphoglycerate. ? CO2 and pH Bohr effect advantage ? Temperature ? 2,3diphosphoglycerate ? CO and the structure of Hb Fully oxygenated hemoglobin releases more protons than the deoxygenated Hb. As a result, in a solution at , the release of 1 mM of O2 from HbO2 permit mM of H+ to be taken up without a change in pH。 thus delivery of O2 aids in buffering acids produced locally in the tissue. 影響氧解離曲線的因素 factors effect oxygen dissociation curve
高考資料相關(guān)推薦
鄂ICP備17016276號-1