動物生理學(xué)5呼吸系統(tǒng)生理上(完整版)
【正文】 ciation curve The position of O2 equilibrium curve can change owing to other physiological factors. The major factors affecting O2 affinity are Pco2, pH, temperature and 2,3diphosphoglycerate. ? CO2 and pH Bohr effect advantage ? Temperature ? 2,3diphosphoglycerate ? CO and the structure of Hb Fully oxygenated hemoglobin releases more protons than the deoxygenated Hb. As a result, in a solution at , the release of 1 mM of O2 from HbO2 permit mM of H+ to be taken up without a change in pH。 T this es mainly from oxidative phosphorylation of glucose which also occurs principally in the mitochondrion. Repiration includes: ? The gases must be moved between the environment and the lungs, usually referred to as “pulmonary ventilation” ? The gases must be exchanged between the spaces in lung and the blood ? Exchange of gases between the blood and the various tissues must occur ? Finally transfer of gases must occur within the tissue to sites of utilization (for O2 ) and from the sites of production (for CO2) pulmonary ventilation Gas exchange between the environment and the lungs, usually referred to as “pulmonary ventilation” The structures needed for pulmonary ventilation: airway, alveoli [230。 生理意義：維持肺泡的穩(wěn)定性；減少肺間質(zhì)和肺泡內(nèi)組織液生成，防止肺水腫；降低吸氣阻力，減少呼吸做功。 thus delivery of O2 aids in buffering acids produced locally in the tissue. 影響氧解離曲線的因素 factors effect oxygen dissociation curve 。 肺容量是指肺容中兩項或兩項以上的聯(lián)合氣量
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