proteinstructures-資料下載頁
【導讀】PROTEINSTRUCTURES. LeftRight. AMINOACID. withadifferent-Rgroup.The20naturally. occurringAmino. Acids.Theshadedboxis. thesameforall. Aminoacids.Itisan. singleCarbonatom. bondedtoanAmino. group,aCarboxyl. Groupanda. Hydrogenatom...R. NH2-C-COOH. H. DisulphideBridge. Thebonds. between. AminoAcids. are…PeptideBonds. Peptidebonds. areformedby. Condensation. andbrokenby. Hydrolysis. APEPTIDEBOND. OH. -C-N-. PRIMARYSTRUCTURE. PIGINSULIN,aproteinhormoneas. SECONDARYSTRUCTURE. TheAlpha. Helix. Right. handed. Left. handed. BetaPleated. Sheet. Thedottedlines. arehydrogen. bondswhich. bindthestrands. together,making. thisastrongflat. fibrousprotein.InSilk,these. sheetsstack. togetherlikea. pileof. corrugatediron.H-bonds. betweenthe. sheetsmakesilk. averystrong. structuralprotein. Poly-L-Proline. Thesestrands. containrepeating. unitsoftheAmino. Acid,Proline.Whenthreesuch. strandswrap. aroundeachother. likeropethey. makeastrong. fibrousprotein,similarto. Collagen.Collagenisfound. inskin,ligaments. andtendons. COLLAGEN. Animportant. ponentof. animalconnective. tissue.Collagenismade. fromthreestrands. consistingmainly. ofGlycineand. Proline...-Gly-Pro-Pro-. repeatedly. wrappedintoa. rope,thewhole. forminganHelix.Natural. Collagenmay. alsohave. someother. AminoAcids. inserted. alongpartsof. thechain.tendonofabird’sneck.tail. TERTIARYSTRUCTURE. themselves.Tertiary. Stucture. Spotthe. Tertiary. folding.Quaternary. Structure. Spotthe. Haemgroup. (Sidechains. havebeen. omittedfor. clarity.). vitalforthecarri
【正文】 in both alpha helices and antiparallel hairpins. Can you see the active site? (Side chains omitted for clarity) LYSOZYME Including the Side chains. Can you see any active site now? CHYMOTRYPSIN A protein digesting enzyme in your stomach. Only the carbon backbone is shown so the secondary structure can be seen. Some parts are twisted into an Alpha Helix. Other parts (in bold) are the straight Beta strands. Spot the Active Site This shows Subtilisin a bacterial enzyme binding with its substrate. The substrate is a short polysaccharide made from six sugar molecules, which is part of the bacterial cell wall. The substrate (in bold) is wedged into its active site and held in place by the Hbonds shown as dotted lines. This is the ‘Enzyme substrate plex’ which forms for a brief moment during any enzyme controlled reaction. ENZYMESUBSTRATE COMPLEX This powerpoint was kindly donated to is home to over a thousand powerpoints submitted by teachers. This is a pletely free site and requires no registration. Please visit and I hope it will help in your teaching.
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