【文章內(nèi)容簡(jiǎn)介】 ugs and Their Synonyms Properties of Organic Solvents Polymers : A Property Database 有機(jī)所圖書(shū)館常用數(shù)據(jù)庫(kù) ?4. 化學(xué)產(chǎn)品目錄數(shù)據(jù)庫(kù) MDL Available Chemical Directory MDL Screening Compounds Directory PJB Pharmaprojects PJB AGROProjects SigmaAldrich Chemical Directory 有機(jī)所圖書(shū)館常用數(shù)據(jù)庫(kù) ?5. 圖書(shū)館館藏目錄 有機(jī)所圖書(shū)館館藏書(shū)刊目錄 全國(guó)期刊聯(lián)合目錄 中科院國(guó)家科學(xué)圖書(shū)館館藏目錄 上海生命科學(xué)圖書(shū)館館藏目錄 上海圖書(shū)館館藏目錄 有機(jī)所圖書(shū)館常用數(shù)據(jù)庫(kù) ?6. 電子期刊全文數(shù)據(jù)庫(kù) ACS 美國(guó)化學(xué)會(huì) (自創(chuàng)刊號(hào) ) RSC 英國(guó)皇家化學(xué)會(huì) (自創(chuàng)刊號(hào) ) Wiley Online Library (部分創(chuàng)刊號(hào) ) Elsevier39。s ScienceDirect (1995 ) Springer SpringerLink (1998 ) Thieme (自創(chuàng)刊號(hào) ) Nature Science 重慶維普中文科技期刊全文數(shù)據(jù)庫(kù) (1989 ) 清華同方中文期刊全文數(shù)據(jù)庫(kù) (1994 ) 有機(jī)所圖書(shū)館常用數(shù)據(jù)庫(kù) ? 7. MDL 系列專(zhuān)業(yè)數(shù)據(jù)庫(kù) CSD (Cambridge Structural Database System) RTECS (Registry of Toxic Effects of Chemical Substances) MDL Available Chemical Directory (Suppliers) MDL Screening Compounds Directory (Suppliers) MDL Comprehensive Medicinal Chemistry MDL Metabolite Database MDL Drug Data Report 3D MDL Reaction Database (ORGSYN, CHC, RLSM, CIRX, SPOR) MDL Toxicity Databse 有機(jī)所圖書(shū)館常用數(shù)據(jù)庫(kù) ?8. ISI 系列數(shù)據(jù)庫(kù) ISI Web of Science (1991 ) ISI BIOSIS Previews ISI Proceedings ISI Derwent Innovations Index ISI MEDLINE ISI INSPEC ISI Journal Citation Reports ISI Essential Science Indicators ISI Current Contents Connect 重點(diǎn)數(shù)據(jù)庫(kù)介紹 ?SciFinder 和 SciFinder Scholar ?CrossFire ?ISI Web of Knowledge ?CCD ?Merck Index ?Pharmaprojects ?Science of Synthesis 及 HoubenWeyl 系列 Beilstein CrossFire 數(shù)據(jù)庫(kù) ?Beilstein 是高質(zhì)量有機(jī)化學(xué)的代名詞 ?Gmelin是高質(zhì)量化學(xué) 數(shù)據(jù) 的代名詞 ?CrossFire簡(jiǎn)介 ?數(shù)據(jù)庫(kù)的檢索 CrossFire system ? Beilstein amp。 Gmelin ? a plete chemical information system ? Client/Server system ? provides a new way of handling chemical information ? Substances (Structures and Properties), Reactions or Citations and provides hyperlinks between the different forms The Database Contents ? literature data 1779 1959, more than million pounds (Beilstein, Basic Series Suppl. IV ) ? literature data 1960 1979, ca. 3 million pounds (Beilstein, Suppl. V ) ? literature data 1979, ca. 5 million pounds, include Pharmacological and Ecological Data, well abstracted ? The yearly growth: ca. structures, reactions and citations The Database Statistics（ BS0604） ?No. of Compounds: 9,780,073 ?No. of Reactions: 10,207,254 ?No. of Citations: 2,049,077 ?Size of Database: 59,033,490,791 byte SciFinder vs CrossFire Sci F i nd er Cros sF i r eC Apl us /R egi s try Be i l st e i n G m e l i nSi nce 1957 1771 1772 197 5 of S ubst a nces 31, 000, 0 00 8, 000, 00 0 1, 400, 00 0 of St r uct ur es 18, 000, 0 00 8, 000, 00 0 1, 400, 00 0 of React i on s 4, 000, 00 0 5, 000, 00 0 n. a.Re f er e nce s 20, 000, 0 00 ? ?Pat ent cov er ag e y es no noFact ua l dat a A v ai l . v i aCA pl us35, 000, 0 00 y esUp dat e dai l y Q uar t er l y ? clos edSciFinder vs CrossFire ? Registry file of SciFinder is the biggest pilation of anic, inanic and anometallic pounds in the world ? Registry is updated daily ? Registry substances e from 8000 journals, while Beilstein covers only 100+ anic journals (now 180) ? Registry contains a lot of substances from patents which CrossFire almost doesn’t ? Gmelin was not updated since around 1990 Beilstein CrossFire 特點(diǎn) ?化合物和反應(yīng)數(shù)量豐富 ?最全面、不可替代的有機(jī)化學(xué)數(shù)據(jù)庫(kù) ?數(shù)據(jù)經(jīng)深加工、高整合 ?可免看原文了解主要概況 ?提供權(quán)威的實(shí)驗(yàn)數(shù)據(jù) ?檢索功能強(qiáng)大 ?應(yīng)用領(lǐng)域廣泛 （尤受制藥研發(fā)推崇） CrossFire 檢索平臺(tái) ?Beilstein ?Gmelin ?Patent Chemistry 從有機(jī)化學(xué)、藥物、染料、生命科學(xué)等相關(guān)專(zhuān)利文獻(xiàn)中收集數(shù)據(jù)和信息，補(bǔ)充 Beilstein的不足，使用戶(hù)獲得的數(shù)據(jù)來(lái)源更趨廣泛和完善。 專(zhuān)利文獻(xiàn) 41萬(wàn)篇 (1978年以后世界、歐洲專(zhuān)利和 1976 年以后美國(guó)專(zhuān)利 ) 化合物 341萬(wàn)個(gè) 反應(yīng) 422萬(wàn)個(gè) CrossFire 化合物 1300萬(wàn)個(gè) + 反應(yīng) 1400萬(wàn)個(gè) DiscoveryGate檢索平臺(tái) ? 是 MDL新一代基于互聯(lián)網(wǎng) Web服務(wù)的化學(xué)綜合信息檢索系統(tǒng) ? 數(shù)據(jù)庫(kù)主要內(nèi)容 Compounds, Reactions amp。 Bibliographic Information Beilstein、 Gmelin、 Patent Chemistry Bioactivity Information Comprehensive Medicinal Chemistry 、 Drug Data Report 、 Metabolite Database 、 Toxicity Database、 National Cancer Institute Database Sourcing amp。 Logistics Information Available Chemical Directory 、 Screening Compounds Directory Synthetic Methodology Information ChemInform Reaction Library 、 Derwent Journal of Synthetic Methods、 ORGSYN Database 、 Reference Library of Synthetic Methodology、 Solid Phase Organic Reactions ? 數(shù)據(jù)庫(kù)網(wǎng)址 Reaxys檢索平臺(tái) ? Reaxys是一個(gè)全新的輔助化學(xué)研發(fā)的在線(xiàn)解決方案，它將著名的CrossFire Beilstein、 Gmelin、 Patent Chemistry 數(shù)據(jù)庫(kù)進(jìn)行整合，并新增更多強(qiáng)大功能。 ? 主要特點(diǎn) 1. 基于網(wǎng)絡(luò)訪(fǎng)問(wèn)，直觀(guān)的、向?qū)降男陆缑?，任何水平的化學(xué)工作者均可輕松使用。 2. 上億條深入的、經(jīng)實(shí)驗(yàn)驗(yàn)證的數(shù)據(jù)；內(nèi)容經(jīng)科學(xué)家們精心篩選，并進(jìn)行深入索引新的數(shù)據(jù)可視化、分析及合成設(shè)計(jì)工具；從檢索結(jié)果到?jīng)Q策輔助，從多步反應(yīng)研究、反向合成分析到合成路線(xiàn)設(shè)計(jì)，均可實(shí)現(xiàn)無(wú)縫對(duì)接。 3. 幫助您識(shí)別有前景的新項(xiàng)目、終止無(wú)效的先導(dǎo)化合物，設(shè)計(jì)經(jīng)濟(jì)、高產(chǎn)率的合成路線(xiàn)，最大限度節(jié)省時(shí)間和成本。 ? 數(shù)據(jù)庫(kù)網(wǎng)址 MDL CrossFire Commander ?Getting Startet ?Search ?Search Result ?Display Hits ?Print and Export ?Settings Commander 的快速入門(mén) ?CrossFire數(shù)據(jù)庫(kù)的三元素 Substance、 Reaction、 Citation ?認(rèn)識(shí) CrossFire 和 Autonom 圖標(biāo) ?選擇數(shù)據(jù)庫(kù) ?學(xué)會(huì) Query Builder 的使用 ?選定化學(xué)結(jié)構(gòu)編輯軟件 ?執(zhí)行檢索和顯示結(jié)果 Query Biulder的使用 ?Text Search all text fields Antimalaria 抗 瘧疾 bibliographic fields Search Option Substances Reactions Citations Query Biulder的使用 ?Field Search Basic Indexes Bibliographic Information Substance Identification Chemical Properties Physical Properties Pharmacological amp。 Ecological Data Query Biulder的使用 (cont.) ? Structure Search as Structure as reactant as product as reagent ? Search Options Free Site: hetero atom / all atom / 指定 Allow: addl. ring / isotopes / charges / radicals… Search AS Stereo OONN檢索實(shí)例 ?TS Cancer Treatment。 Antimalaria。