20xx年泰山醫(yī)學(xué)院大學(xué)生科研基金項(xiàng)目申請(qǐng)書(shū)指導(dǎo)教師畢玉水(編輯修改稿)
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【文章內(nèi)容簡(jiǎn)介】 可明顯增加到 100200 ppm，臨床上可通過(guò)檢測(cè)呼吸氣中的氫水平用來(lái)診斷上述疾病。氫氣在體抗氧化作用的發(fā)現(xiàn) ，提示我們需要重新評(píng)價(jià)人體內(nèi)氫的生物學(xué)效應(yīng)。 總之，氫氣具有選擇性抗氧化作用的發(fā)現(xiàn)，具有十分重要的意義，不僅會(huì)引起基礎(chǔ)和臨床醫(yī)學(xué)領(lǐng)域的很大興趣，而且可能對(duì)人類(lèi)疾病的防治產(chǎn)生深遠(yuǎn)影響。但由于該領(lǐng)域的研究深度和廣度有限，目前尚難以進(jìn)行更加全面清晰的描述和準(zhǔn)確推測(cè)。我們將不斷關(guān)注和總結(jié)該領(lǐng)域的更新和發(fā)展，也希望有更多人對(duì)氫分子醫(yī)學(xué)引起關(guān)注。 6 主要參考文獻(xiàn) 1. Buxton GV, Greenstock CL, Helman WP, Ross AB. Critical review of rate constants for reactions of hydrated electrons, hydrogen atoms and hydroxyl radicals in aqueous solution[J]. J Phys 。17:513–886. 2. Kayar SR, Axley MJ, Homer LD, Harabin AL. Hydrogen gas is not oxidized by mammalian tissues under hyperbaric conditions[J].Undersea Hyperb Med. 1994。 21:265275. 3. Dole M, Wilson FR, Fife hydrogen therapy: a possible treatment for cancer[J]. 。190:152154. 4. Gharib B, Hanna S, Abdallahi OM, Lepidi H, Gardette B, De Reggi M. Antiinflammatory properties of molecular hydrogen: investigation on parasiteinduced liver inflammation[J].C R Acad Sci III. 2020。 324:719724. 5. Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, Yamagata K, et al. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals[J]. Nat Med. 2020。 13: 688694. 6. Katherine C, Wood, Mark T Gladwin. The hydrogen highway to reperfusion therapy[J]. Nat Med. 2020。13: 673674. 7. Singhal AB, Lo in emerging nondrug therapies for acute stroke 2020[J]. Stroke. 2020。39(2):289291. 8. Sun XJ, Zhang JH. Hydrogen an endogenous antioxidant in the body[J]. 第二軍醫(yī)大學(xué)學(xué)報(bào) . 2020。 29: 233235. 9. Fukuda KI, Asoh S, Ishikawa M, Yamamoto Y, Ohsawa I, Ohta S. Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress[J]. Biochem Biophys Res Commun. 2020。 361: 670674 10. Hayashida K, Sano M, Ohsawa I, Shinmura K, Tamaki K, Kimura K, et al. Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemiareperfusion injury[J]. Biochem Biophys Res Commun. 2020。373:3035. 11. Ohsawa I, Nishimaki K, Yamagata K, Ishikawa M, Ohta S. Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice[J].Biochem Biophys Res Commun. 2020。 377:11951198 12. Kajiyama S, Hasegawa G, Asano M, Hosoda H, Fukui M, Nakamura N, et al. Supplementation of hydrogenrich water improves lipid and gluc
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