【文章內容簡介】 se)
　　(掌聲)
　　Not so fast, Iamp。rsquo。m , thatamp。rsquo。s not the . And why?Itamp。rsquo。s because human genetics has taught usthat when it es to our telomerase,we humans live on a knife , simply put,yes, nudging up telomerase does decrease the risks of some diseases,but it also increases the risks of certain and rather nasty even if you could buy that Costcosized bottle of telomerase,and there are many websites marketing such dubious products,the problem is you could nudge up your risks of we donamp。rsquo。t want that.
　　很抱歉，沒那么快。唉，并不是那樣的。那為什么呢?因為人類遺傳學教導我們，談到我們的端粒酶時，我們人類是住在刀緣上的。簡單來說，是的，增加端粒酶的確可以減少一些疾病的風險，但同時也會增加某些很糟糕的癌癥的風險。所以，就算你能買到像好市多那樣超大罐的端粒酶，有許多網站在行銷這類可疑的產品，問題是你有可能增加罹癌的風險。我們不想要那樣。
　　Now, donamp。rsquo。t worry,and because, while I think itamp。rsquo。s kind of funny that right now,you know, many of us may be thinking,well, Iamp。rsquo。d rather be like pond scum.
　　別擔心，因為，雖然我覺得有點好笑，也許此刻很多人正想著，我寧可像池塘浮渣一樣。
　　(Laughter)
　　(笑聲)
　　There is something for us humansin the story of telomeres and their I want to get one thing isnamp。rsquo。t about enormously extending human lifespanor amp。rsquo。s about health , health span is the number of years of your lifewhen youamp。rsquo。re free of disease,youamp。rsquo。re healthy, youamp。rsquo。re productive,youamp。rsquo。re zestfully enjoying span, the opposite of health span,is the time of your life spent feeling old and sick and the real question bees,OK, if I canamp。rsquo。t guzzle telomerase,do I have control over my telomeresamp。rsquo。 lengthand hence my wellbeing, my health,without those downsides of cancer risks?OK?
　　在這關于端粒以及維護端粒的真相中還是有我們人類可以學習之處。但我想先澄清一件事。重點并不是將人類壽命期間延長很多或是永生不死。重點是「健康期間」。健康期間，就是你人生中有多少年是沒有疾病、很健康、有生產力、能夠熱情享受人生的。相對于健康期間的「疾病期間」，指的就是你人生中有多長時間覺得自己老、病、和垂死。所以，真正的問題變成是，如果我無法狂飲端粒酶，我是否能控制端粒酶的長度，進而控制我的福祉、我的健康，而沒有癌癥風險的壞處?好嗎?
　　So, itamp。rsquo。s the year , Iamp。rsquo。ve been minutely scrutinizing little teeny tiny telomeresvery happily for many years,when into my lab walks a psychologist named Elissa , Elissaamp。rsquo。s expertise is in the effects of severe, chronic psychological stresson our mindamp。rsquo。s and our bodyamp。rsquo。s there she was standing in my lab,which ironically overlooked the entrance to a mortuary, and
　　所以，那是 2020 年。多年來，我很快樂地、分分鐘鐘地持續(xù)仔細觀察著那些極微小的端粒，直到有一天，名叫伊莉莎埃佩爾的心理學家走入了我的實驗室。伊莉莎的專長在于嚴重慢性心理壓力對于我們身、心健康的影響。她出現在我的實驗室，很諷刺的是從實驗室可以眺望停尸間的入口，而且──
　　(Laughter)
　　(笑聲)
　　And she had a lifeanddeath question for happens to telomeres in people who are chronically stressed?she asked see, sheamp。rsquo。d been studying caregivers,and specifically mothers of children with a chronic condition,be it gut disorder,be it autism, you name it a group obviously under enormous and prolonged psychological have to say, her questionchanged me , all this time I had been thinking of telomeresas those miniscule molecular structures that they are,and the genes that control when Elissa asked me about studying caregivers,I suddenly saw telomeres in a whole new saw beyond the genes and the chromosomesinto the lives of the real people we were Iamp。rsquo。m a mom myself,and at that moment,I was struck by the image of these womendealing with a child with a conditionvery difficult to deal with,often without such women, simply,often look worn was it possible their telomeres were worn down as well?
　　她有個生死問題要問我。「有慢性壓力的人，他們的端粒會發(fā)生什么事?」她這樣問我。她一直在研究照護者，特別慢性病孩童的母親，可能是腸病，可能是自閉癥，任何你想得到的──這個族群很顯然處在巨大且長期的心理壓力之下。我不得不說，她的問題深深改變了我。一直以來，我從小分子結構的角度來思考端粒和控制端粒的基因。當伊莉莎問我關于照護者的問題時，我突然從全