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teps and control measures Hazard identification and determination of acceptable levels Establish OPRPs Hazard assessment Selection and assessment of control measures Establish HACCP plan Validation of control measures Verification planning Prerequisite programs (PRPs) Documentation Verification Implementation Monitoring Nestl233。 Research Center Nov 6 2021 NRCQS, M Peterz 2 ? Overview – Prerequisite Programs – Operational Prerequisite Programs – Hazard analysis HACCP and ISO 22021 Nestl233。 Research Center Nov 6 2021 NRCQS, M Peterz 10 What is an operational prerequisite program? ? OPRPs are PRPs that are essential because the hazard analysis has shown that they are necessary in order to control specific food safety hazards ? OPRPs are used to reduce the likelihood that products and/or the processing environment – will be exposed to hazards, – will be contaminated, – and that hazards will proliferate. Operational prerequisite programs (OPRPs) Nestl233。 Research Center Nov 6 2021 NRCQS, M Peterz 18 OPRP or CCP (HACCP plan)? A decision tree has been developed to assist in the categorization of control measures Distinction is mainly based on … ? … its place in the system ? … the possibility to establish critical limits ? … whether corrections can be taken immediately when there is a loss of control Nestl233。對健康影響的嚴(yán)重性發(fā)生可能性。 Research Center Nov 6 2021 NRCQS, M Peterz 20 Decision tree (2) ?Answer each question for each hazard and step in the process. ?Q1 refers to the oute of the hazard assessment. ?Q2 – Q5 is used to categorize control measures, according to whether they are managed by an OPRP or in the HACCP plan at CCPs. YES Q5: Is it possible to monitor the control measure in such a way that corrective actions can be taken immediately when there is a loss of control? Q4: Is it possible to establish critical limits for the control measure at this step? YES This hazard is managed by an OPRP. This hazard is managed by the HACCP plan (CCP). NO NO YES Nestl233。 Research Center Nov 6 2021 NRCQS, M Peterz 12 Operational prerequisite programs (OPRPs) Are OPRPs something new? ? We have applied the concept of OPRPs since long (they are managed as CPs in the QMS) ? These are the PRPs/GMPs identified