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心電學預(yù)警心衰猝死的風險(存儲版)

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【正文】 nomic index, which included BRS and timedomain measures of HRV, increased the relative risk to 8. A smaller number of studies of patients with nonischemic dilated cardiomyopathy, chronic congestive heart failure, or hypertrophic cardiomyopathy (HCM) and patients undergoing revascularization have also suggested a predictive value of heart rate turbulence. ? In the Marburg Cardiomyopathy Study of 242 patients with nonischemic dilated cardiomyopathy, heart rate turbulence onset was a multivariate predictor of transplantfree survival (relative risk , 95% CI to ) but not of arrhythmic events. A, et al. Am J Cardiol. 2020。356:651–652. (九)竇性心率震蕩 ? 定義 :正常人,當自主神經(jīng)功能正常時,一次室早后常有竇性心律先加速,后減速的雙相式變化,這種現(xiàn)象稱為竇性心率震蕩( Heart Rate Tuburlence,HRT)。 ? 首先發(fā)表的作者: Mines GR ( Italy), J Physiol. 1913 46 :349; Smith JM ( USA), Circulation, 1988, 77: 110 ? 檢測對象 : 心肌的復(fù)極異常和心肌的易損性 ? 檢測方法 : 頻域法; 時域法 ? 正常值 : 1. 常規(guī)心電圖判斷顯性 T波電交替陽性參考標準: 同一導聯(lián) T波的形態(tài)、振幅、極性出現(xiàn)逐搏交替變化,其中 T波振幅逐搏相差 ≥。 ? 檢測方法 : 選最大 QT(QTmax)、最小 QT(QTmix)導聯(lián)連續(xù)測量三個心動周期,取其平均 值為 QTmax、 QTmix間期,然后計算: QTd=QTmax QTmin. ? 正常值 :目測 QTd:正常參考值< 50ms, 50~ 70ms 之間有參考價值,以> 70ms有診斷價值。 1977 ? 檢測原理 :由于這種電信號非常微弱,一般在幾十微伏以下,故常規(guī)心電圖難以捕捉到,信號平均心電圖( SAECG)則可以記錄到該電活動信號。 however, low HRV did not predict arrhythmic mortality. ? Abundant data show that depressed HRV is a predictor of total mortality. Despite the theoretical pathophysiological link among abnormal HRV, autonomic tone, and arrhythmogenesis, the present data show that HRV may be a better marker of nonarrhythmic mortality. AJ, et al. Circulation. 2020。 87: 814 ? 檢測對象 : 自主神經(jīng)功能變化 ? 檢測方法 : 時域法 ,頻域法 ,非線性分析法 長時程( 24h)分析 , 短時程( 5min)分析 ? 正常值 : ① SDNN: 100 ms,② SDANN: 127177。94: 3198–3203. ? In pts with nonischemic cardiomyopathy and congestive heart failure, LVEF 35%, and ventricular arrhythmias (NSVT or an average of 10 or more VPBs per hour), DEFINITE demonstrated a trend toward improvement in overall survival (hazard ratio , 95% CI to , P ) and a reduction in arrhythmic events (hazard ratio , 95% CI to ,P ) with ICD therapy. The mortality rate of the nonICD group was 7% per year, but no parison group of pts without ventricular arrhythmias was reported. (三)心率恢復(fù)和恢復(fù)性室性異位搏動 ? Immediately after graded exercise,heart rate normally falls in a biphasic manner, with an initial rapid decline occurring during the first 30 seconds to 1 minute of recovery. ? Imai K,et al. demonstrated that this initial steep descent is marked in athletes and attenuated in pts with heart failure and that it can be eliminated by administration of atropine. [1] ? The ideal recovery protocol and abnormal cutoff value are unclear。18:12691275. 10 20 30 40 50 60 70 80 90 100 0 1 2 3 4 5 6 7 8 9 % Success *Nonlinear Time (minutes) 成功減少的幾率 7 10% 每分鐘! 一、心臟猝死的概況 (四) SCD 的克星 — ICD ? 對猝死的征服中, ICD已邁出了第一步 MICHEL MIROWSKI, Oct 14 1924 Mar 26 1990 conceived of ICD in the 1960s The first human implant in 1980 ICD 放電 一、心臟猝死的概況 二、影響 SCD 危險因素及 相關(guān)檢測方法 自主神經(jīng)系統(tǒng) HRV BRS HRT 運動后心率恢復(fù) 心肌基質(zhì) SAECG LVEF QRS時限 QTc QT d TWA 心肌易損性 二、影響 SCD 危險因素 三、常用的 SCD危險分層檢測方法 1)心率變異性 ( HRV) 2)壓力反射敏感性試驗 ( BRS ) 3)心室晚電位( SAECG ) 4) QT 離散度( QTd ) 5)
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