小時(shí)糖耐量試驗(yàn)的臨床意義-預(yù)覽頁(yè)
【正文】 IGT Known DM New DM 29% 35% 22% 22% 31% 30% 15% 10% 3% 3% 0 20 40 60 80 100 % Acute Elective The DECODE Study ( Diabetes Epidemiology: Collaborative analysis Of Diagnostic criteria in Europe 2hour plasma glucose (mmol/l) – ? Total – 21,968 2,020 2,562 893 316 206 24,846 3,119 ? 276 378 489 1,143 Fasting plasma glucose (mmol/l) Total 24,264 3,833 1,011 29,108 Adapted from DECODE Study Group. Br Med J 1998。 I G TI G TI F G 3039 4049 5059 6069 7079 8089 Prevalence (%) of IGT but not IFG increases with age in DECODE population The DECODE group, Diabetes Care 2022。 47: 385394 Hazard ratio for mortality by 2hPG categories, the DECODA Study 2hPG (mmol/l) (n=4753) (n=1106) ? (n=447) P for trend CVD Model 1 Model 2 1 1 () () () () Allcause Model 1 Model 2 1 1 () () () () Model 1: Adjusted for age, sex, cohort, BMI, sysBP, Chol and smoking Model 2: Additional adjustment for FPG DECODA Study Group, Diabetologia 2022。 152:2738 STOPNIDDM Trial (1) 0 0 , 2 0 , 4 0 , 6 0 , 8 1 1 , 2 1 , 4Myocardial infarction Angina Revascularization procedure Cardiovascular death Cerebrovascular event or stroke Peripheral vascular disease Any cardiovascular event Favours Acarbose Favours Placebo Chiasson JL JAMA 2022。353:2643 Participants: 1394 (97% of the original cohort) DCCT participants Oute: Nonfatal MI or stroke。 OR revascularization Followup: Until 50 conventional pts CV event 11 yrs post DCCT。 CVD: T1 DM DCCT/EDIC NEJM 2022。1994 BMJ Publishing Group Ltd. McCane, D R et al. BMJ 1994。 161:397404 Adjusted for age, center, sex, cholesterol, BMI, BP, smoking TiQeNbJ8G5D1Ax*t$qYnVkSgPdMaI7F3C0z) vamp。t!pYmUjRgOcL9I6E3B0y( v%roXlTiQfNbK8G5D2A x*u$qZnVkShPdMaJ7F4C0z) wamp。t!qYmVj SgOdL9I6F3B0y) v%soXlUi QfNcK8H5D2A+ x*u$r ZnWkShPeM aJ7G4C1z) wamp。spXmUiRfOcK9H5E2B+ x(u%rZoW kThQeMbJ8G4D1z w*t!qYnVjSgPdLaI6F3C0y) vamp。t!pYmUjRgOcL9I6E3B+ y( v%roXl TiQeNbK8G5D2Ax*t$qZnVkShPdMaI7F4C0z) wamp。s!pXmUiRfOcK9H6E2B+ x(u%rZoWlThQeMbJ8G4D1A w*t!qYnVjSgPdLaI7F3C0y) vamp。s!pYmUjRfOcL9H6E3B+ y(u%roWlTiQeNbJ8G5D1A x*t$qZnVkSgPdMaI7F4C0z) vamp。t!qYmVjSgOdL9I6F3B0y) v%soXl UiQfNcK8H5D 2A+ x*u$rZnWkShPeMaJ7G4C1z) wamp。spXmUiRfOcK9H6E2B+ x( u%rZoWlThQeMbJ8G4D1Aw*t!qYnVjSgPdLaI6F3C0y)vamp。t!pYmUjRgOcL9I6E3B*u$rZnWkThPeMaJ7G4C1z wamp。s!pXmUiRfOcK9H6E2B+ y(u%rZoWlThQeNbJ8G4D1A w*t$qYnVjSgPdLaI7F3C0y) vamp。s!pYmUjRgOcL9H6E3B+ y( v%roWlTiQeJ7G4C 1z) wamp。spXmUi RfOcK9H5E2B+ x(u%rZoWkThQeMbJ8G4D1z w*t!qYnVjSgOdLaI6F3C0y) vamp。s!pYmUjRgOcL9I6E3B+ y( v%roXlTiQeNbK8G5D2A x*t$qZnVkShPdMaI7F4C0z) wamp。s!pXmUiRfOcK9H 6E2B+ x(u%rZoWlThQeMbJ8G4D1A w*t!qYnVjSgPdLaI6F3C0y) vamp。t!pYmVjRgOcL9I6E3B0y( v%roXl TiQfNbK8G5D 2A x*u$qZnVkShPdMaJ7F4C0z) wamp。t!qYmVjSgOdL9I6F3B0y) v%soXlUiQfNcK8H 5D2At!qYnVjSgOdLaI6F3C0y) v%spXlUiR fNcK8H5E2A+ x(u$rZoWkThPeMbJ7G4D 1z wamp。s!pXmUjRfOcL9H6E2B+ y(u%roWlThQeNbJ8G5D1A w*t$qYnVkSgPdLaI7F3C0z)
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