20xx年醫(yī)學(xué)專(zhuān)題—神經(jīng)病性疼痛和輔助鎮(zhèn)痛劑的意義-全文預(yù)覽
【正文】 ntin）.,第二十頁(yè)，共三十二頁(yè)。,抗焦慮劑（咪達(dá)唑侖174。) 米氮平,第十六頁(yè)，共三十二頁(yè)。) 阿米替林 imipramine (Tofranil174。,我們(wǒ men)將討論哪些藥物？ About which drugs we are talking about?,Antidepressants 抗抑郁劑 Anxiolytics 抗焦慮劑 Anticonvulsants 抗驚厥藥物 NMDA inhibitors N甲基D天冬氨酸抑制(y236。ngt242。,第十一頁(yè)，共三十二頁(yè)。)性損害,True neuropathic pain 真性神經(jīng)病性疼痛 damage irreversible 不可逆損傷 central sensitization (spinal cord, brain) 中樞神經(jīng)(zhōngshūsh233。)過(guò)敏,第七頁(yè)，共三十二頁(yè)。,神經(jīng)病性疼痛(t233。ngji233。u)傷害性的疼痛 Nociceptive pain,第三頁(yè)，共三十二頁(yè)。,“自然(z236。)鎮(zhèn)痛劑的意義 Neuropathic pain and the meaning of adjuvant analgesics,Dr. Z. Zylicz Hospice in the Weald Pembury, Tunbridge Wells Kent, UK,第一頁(yè)，共三十二頁(yè)。,感受(gǎnsh242。ng) Inflammatory pain,痛覺(jué)(t242。,“病理性疼痛” 與適應(yīng)性無(wú)關(guān) “病理性疼痛”，“沒(méi)有目的的疼痛” 常常是神經(jīng)病性源性 對(duì)經(jīng)典(jīngdiǎn)鎮(zhèn)痛劑沒(méi)有或部分敏感 對(duì)輔助鎮(zhèn)痛劑常常敏感 “pathologic pain” has nothing to do with adaptation “pathologic pain”, “pain without purpose” frequently of neuropathic origin, not or only partially sensitive to classical analgesics frequently sensitive to adjuvant analgesics,第六頁(yè)，共三十二頁(yè)。ngji233。ng)的2種類(lèi)型 Two types of neuropathic pain,Neurogenic pain 神經(jīng)源性疼痛 pressure on the nerve 神經(jīng)受壓迫 peripheral sensitization 外周神經(jīng)敏化 Reversible可逆轉(zhuǎn)性 distal to the damage 末稍損傷 partially sensitive to analgesics 對(duì)鎮(zhèn)痛劑部分敏感 responds to local anaethetics 對(duì)局部麻醉劑有反應(yīng) nerve entrapment 神經(jīng)的壓迫(yāp242。,第十頁(yè)，共三十二頁(yè)。,“輔助性鎮(zhèn)痛劑…” 所有的藥物，包括尚未被許可用于治療疼痛(t233。 “Adjuvan
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