【正文】
tment,Supportive cares and preparation of the patients. Antileukemic therapy. Therapy of the central nervous system. Stem cell transplantation.,第四十八頁,共七十二頁。nbi233。,第四十二頁,共七十二頁。,第三十八頁,共七十二頁。,免疫(miǎny236。,第三十三頁,共七十二頁。,Diagnosis amp。,Marrow findings,Normal bone marrow,AML marrow,第二十七頁,共七十二頁。,第二十四頁,共七十二頁。,臨床表現(xiàn),第二十頁,共七十二頁。,第十六頁,共七十二頁。Pathogenesis,Environmental factors Acquired diseases,Lesions to the DNA,Clonal expansion,第十二頁,共七十二頁。,第十頁,共七十二頁。,Pluripotential stem cells,Myeloid stem cells,Lymphoid stem cells,Unipotential progenitor cells,Immature hematopoietic cells,mature hematopoietic cells,第六頁,共七十二頁。i sh249。ng)白血病FAB分型,聯(lián)合化療的原則,完全緩解的概念。d236。)數(shù):3學(xué)時(shí)(xu233。第六篇 血液(xu232。sh237。,講授目的(m249。x236。u)主要內(nèi)容,概述(ɡ224。,Erythrocytes: transport oxygen,Neutrophil Basophil Eosinophil Monocytes/Macrophage,Defense against infection,Platelets: Mediate blood clotting,Tlymphocytes: antigen presenting,Blymphocytes Plasma cell:,Source of antibodies,第五頁,共七十二頁。,第九頁,共七十二頁。,Etiologyamp。,Inherited syndromes such as ataxiatelangiectasia, down syndrome predispose to subsequent development of leukemia. Usually, these kinds of syndromes share the common features that they all have heretic defects in their genome gave by their parents.,第十五頁,共七十二頁。,Myelogenous versus lymphocytic leukemia,If the leukemic cells arise from myeloid pluripotential stem cells: myeloid leukemia,If the leukemic cells arise from lymphocytic pluripotential stem cells: lymphocytic leukemia,第十九頁,共七十二頁。,Infiltrations,Oral tissue: swollen painful, and bleeding gums. Splenomegaly and hepatomegaly. Lymph node enlargement. Bone or joint pain. CNSheadaches, seizures, weakness, blurred vision and vomiting.,第二十三頁,共七十二頁。,Blood test findings Anemia is a constant feature.Nucleated red cells or immature red blood