抗寄生蟲藥antiparasitedrugs——方三華-全文預(yù)覽
【正文】 播 Primaquine （伯 氨喹 ） Chloroquine （ 氯喹 ） Quinine （奎寧） （ 惡 性 瘧 無效） 病因 預(yù) 防 Pyrimethamine (乙 胺嘧啶 ) 速 發(fā) 阻止 傳 播 Pyrimethamine （乙 胺嘧啶 ） ? 用于控制癥狀的抗瘧藥 Chloroquine （氯喹） 、 Quinine （奎寧）、 Mefloquine （甲氟喹）、 Pyronaridine (咯萘啶 )、Artemisinin (青蒿素 ) 、 Artemether and artesunate (蒿甲醚和青蒿琥酯 ) ? 用于控制復(fù)發(fā)和傳播的抗瘧藥 Primaquine （伯氨喹） ? 用于病因性預(yù)防的抗瘧藥 Pyrimethamine （乙胺嘧啶） Antiamebiasis drugs ?Amebiasis is infection with Entamoeba histolytica. （溶組織內(nèi)阿米巴原蟲 ） Classification of amebiasis ?Asymptomatic intestinal infection。 and include seizures and damage of nerves resulting in numbness and tingling of extremities (peripheral neuropathy). ?Minor side effects include nausea, headaches, loss of appetite, a metallic taste, and rarely a rash. Antiamebiasis drugs Metronidazole Emetine依米丁 amp。 ? Others include nausea, vomiting, abdominal pain, pruritus, urticaria, arthralgia, myalgia, and lowgrade fever. ? Mild and transient elevations of liver enzymes Praziquantel 吡喹酮 Filariasis ? 淋巴管炎、淋巴結(jié)炎 ? 橡皮腫、乳糜尿 Diethylcarbamazine 乙胺嗪 Anthelmintic Actions Diethylcarbamazine immobilizes microfilariae （ 微絲蚴） and alters their surface structure, displacing them from tissues and making them more susceptible to destruction by host defense mechanisms. Clinical Uses Wuchereria Bancrofti, Brugia Malayi, Brugia Timori, and Loa Loa Adverse effects Generally mild and transient Include headache, malaise, anorexia, weakness, nausea, vomiting, and dizziness. Anthelmintic Drugs 驅(qū) (蠕 )蟲藥 Anthelmintic Drugs –Albendazole （阿 苯達(dá)唑 ） Pharmacological effects ?A broadspectrum oral anthelmintic, is the drug of choice for treatment of hydatid disease （包蟲病）and cysticercosis. （囊蟲?。? ?Also used for the treatment of pinworm （蟯蟲）and hookworm infections, ascariasis（蛔蟲?。? , trichuriasis（鞭蟲?。?and strongyloidiasis（類圓線蟲?。? Anthelmintic Drugs Albendazole Adverse effects ?Mild and transient epigastric distress, diarrhea, headache, nausea, dizziness, lassitude, and insomnia can occur. ?Abdominal distress, headaches, fever, fatigue, alopecia, increases in liver enzymes, and pancyt
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