【正文】
5d 聯(lián)合或序貫 VB1 100mg Qd po ?大劑量方案: VB1 500mg tid im/iv 阿德福韋不良反應(yīng) ?In patients with pensated liver disease, the most monly reported side effects were asthenia, headache, abdominal pain, and nausea during 48 weeks of therapy. In patients with depensated liver disease, the most monly reported side effects were increased creatinine and asthenia during up to 203 weeks of therapy. ?Renal: Very mon (10% or more): Increased serum creatinine; Common (1% to 10%): Renal failure, abnormal renal function; Frequency not reported: Renal toxicity, changes in renal function, renal events, renal insufficiency, renal calculus, renal pain, nephrotoxicity, Fanconilike syndrome, overall renal function deterioration;Postmarketing reports: Proximal renal tubulopathy, Fanconi syndrome ?Other: Very mon (10% or more): Asthenia (up to 13%), decreased serum phosphorus;Common (1% to 10%): Decreased carnitine levels