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后第一年內(nèi)[16],且死亡率隨著年齡遞增[17]。 髖部骨折主要包括股骨頸骨折和股骨粗隆間骨折,其危害性遠大于其它部位的骨折,而且需要更多的衛(wèi)生保健資源[13]。年齡相關(guān)的骨強度減弱是髖部骨折隨增齡增加的主要原因。徐棟梁等[7]對廣州地區(qū)60歲以上老年人群骨質(zhì)疏松性骨折的調(diào)查表明,%,%。在美國50歲以上白種女性髖部骨折終身危險高達17%,與之相比50歲以上白種男性僅僅是6%,所以其在西方白人婦女中是與骨質(zhì)疏松癥相關(guān)的脆性骨折發(fā)病最多,死亡率最高的一類。Li等[2] 采用分層多階段整群抽樣方法對中國五大行政區(qū)的40歲以上人群進行調(diào)查,采用DEXA 測量BMD,按照WHO的診斷標(biāo)準(zhǔn),研究發(fā)現(xiàn)骨質(zhì)疏松癥患病率(POP)%,%,%,兩者之間差異有非常顯著性。根據(jù)美國第3次全國營養(yǎng)與健康調(diào)查(1988~1994年),全國50歲以上的男性和女性骨質(zhì)疏松癥患病率分別為3%~6%和13%~18%。變異系數(shù)寧夏醫(yī)學(xué)院碩士研究生學(xué)位論文 目錄目錄研究背景................................................................................................................................1參考文獻...............................................................................................................................4第一部分 寧夏回族正常人群骨密度及骨質(zhì)疏松患病率研究前言................................................................................................................................6對象和方法.....................................................................................................................7結(jié)果................................................................................................................................ 9討論................................................................................................................................13結(jié)論................................................................................................................................16參考文獻.........................................................................................................................17第二部分 寧夏地區(qū)髖部骨折流行病學(xué)分析前言................................................................................................................................19對象和方法.............................................................................................................20結(jié)果................................................................................................................................21討論................................................................................................................................35結(jié)論................................................................................................................................40參考文獻........................................................................................................................41綜述............................................................................................................ .............................45綜述參考文獻........................................................................................... ..............................51致謝.................................................................. ......................... ..................... ..................... 54攻讀學(xué)位期間發(fā)表的學(xué)位論文..................... ..................... ..................... ..................... .... 55個人簡歷.... .... .... .... .... .... .... .... .... .... .... .... .... .... .... .... .... .... .... .... .... .... .... .... .... ....56寧夏醫(yī)學(xué)院碩士研究生學(xué)位論文 研究背景研究背景 骨質(zhì)疏松癥(osteoporosis,OP)是一組全身性的骨骼疾病,其特征是骨密度、強度下降、骨折風(fēng)險性增加[1]。破骨細胞WHO world health organization osteoblast 骨峰值BMI Bone mineral density。177。 股骨頸。女性髖部骨折,不管是股骨頸骨折還是粗隆間骨折,在絕經(jīng)期以后急劇上升,%。50歲以下男性發(fā)病多于女性,50歲以上女性明顯增加并超過男性。方法 收集寧夏地區(qū)20012006年髖部骨折出院病例,設(shè)計調(diào)查表進行相關(guān)因素的登記,對髖部骨折的流行特征及6年發(fā)生情況進行動態(tài)分析。關(guān)鍵詞 骨質(zhì)疏松癥。結(jié)果 (1)男女性BMD峰值均出現(xiàn)于30~39歲組, 177。寧夏醫(yī)學(xué)院碩士研究生學(xué)位論文 寧夏地區(qū)骨質(zhì)疏松癥及骨質(zhì)疏松性骨折的流行病學(xué)研究 寧夏醫(yī)學(xué)院研究生部寧夏醫(yī)學(xué)院碩士研究生學(xué)位論文 目錄Ningxia Medical CollegeThesis for Application of Master Degree Epidemiological Study onOsteoporosis and Osteoporotic fracture in NingXia Student Name: Ma ZongjunDirector:Wang Yinong ProfSpecialty: Spine SurgeryMajor: OrthopaedicsFinish Date: Apr. 2008寧夏醫(yī)學(xué)院碩士研究生學(xué)位論文 中文摘要寧夏地區(qū)骨質(zhì)疏松癥及骨質(zhì)疏松性骨折的流行病學(xué)研究摘 要第一部分 寧夏地區(qū)回族正常人群骨密度及骨質(zhì)疏松患病率研究目的 調(diào)查寧夏地區(qū)回族正常人群骨密度值及骨質(zhì)疏松患病率,建立寧夏地區(qū)回族人群各年齡組的骨密度正常值范圍為骨質(zhì)疏松的預(yù)防提供科學(xué)依據(jù)。177。 骨密度。對比分析股骨頸骨折與粗隆間骨折的流行病學(xué)特征及相關(guān)因素。左側(cè)略多于右側(cè)(:1,:1),以從事體力勞動者多見,骨折的原因分析中主要為輕傷(跌倒扭傷占73. 4496);髖部骨折發(fā)生季節(jié)以冬季為高發(fā)季節(jié)。此類患者多數(shù)年老體弱、合并內(nèi)科疾病,髖部骨折的治療以手術(shù)為主。 粗隆間。, and BMD decreased with age。 Hui people, PrevalencePart Ⅱ Epidemiological study on Hip Fractures in NingXiaObjective To study the epidemic characteristics of hip fracture and analyze the epidemiology of femur neck and trochanteric hip fractures in Ningxia from 2001 to 2006. Methods The cases of hip fractures in Ningxia Provincial Hospital and the First Affiliated Hospital of Ningxia Medical College were collected from 2001 to 2006. Questionnaires were designed to fill with the corresponding information which were considered in our study. Epidemiologic features and correlation factors were pared and analyzed between femur neck and trochanteric hip fractures. Results 756 cases (397 for males and 359 for females) were collected,femur neck fractures were 432 and intertrochanteric fractures were 324 , respectively. The left of hip tends to be more breaker than the right. The old people were susceptible to hip fractures mostly. The avarage age of hip fractures is years old. The incidence of both transcervical and pertrochanteric hip fractures increased significantly among people over 60 years. The difference in general distribution was not obvious between male and female,but male cases predominated in the cases before the age of 50, and women aged above 50 years old suffered from the hip fracture were more than those of men. The mean age of all intertrochanteric fiactures was years older than that of femoral neck fractures. It was more mon in those who engaged in manual labor than those who in brainwork. Slight injures were t