肺心病英文中山大學內(nèi)科學(已修改)
2025-02-01 11:13 本頁面
【正文】 Chronic Pulmonary Heart Disease The second affiliated hospital of Sun Yatsen university, pulmonary department. Shanping Jiang OUTLINE ?Definition ： Chronic lung,chest or pulmonary vascular diseases→Pulmonary vascular resistance ↑ → Pulmonary artery pressure↑ → Hypertrophy and dilatation of the right ventricle →Right Heart Failure ?Prevalence： %～ % ?Onset ages：＞ 40 years old ?Incidence season： Winter and Spring ?Predisposing factors ： Acute respiratory infections Etiology ?Chronic bronchial and lung diseases： the most mon disease is Chronic obstructive pulmonary disease ＞ 80% ?Thoracic deformity ?Pulmonary vascular disorders ?Others Mechanism and Pathology （一） Pulmonary hypertension： Definition ： mean pulmonary artery pressure （ mPAP） ≥ 25 mmHg at rest or ≥ 30 mmHg during exercise. ?Functional changes in pulmonary vascular ? Hypoxia, Hypercapnia, Respiratory acidosis, vasoconstriction substances→Pulmonary vasoconstriction→Pulmonary hypertension ? Hypoxia is the most important factor leads to pulmonary hypertension ?Anatomic changes in pulmonary vascular ? Remodeling of pulmonary vessels ?Increased blood viscosity and blood volume Mechanism and Pathology （二） Dysfunction of right heart Pulmonary hypertension → Afterload of right ventricular ↑, Oxygen supply of myocardium ↓ → Hypertrophy and dilatation of the ri
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