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【正文】 r specificity is useful in the case of an enzyme like papain which is important in protein digestion. It can catalyze the hydrolysis of peptide (amide) bonds in a variety of proteins, which means that the body does not need to maintain a stock of more specific enzymes to tackle specific proteins.這個(gè)廣泛的特異性在酶中很有用,例如木瓜蛋白酶,它在蛋白質(zhì)消化中具有重要意義。木瓜蛋白酶可以在各種蛋白質(zhì)中催化肽鍵的水解,從而可使人體不需要更高特異性酶來(lái)專門水解特殊的蛋白質(zhì)。8. Thus we can describe them in terms of their primary, secondary, tertiary, and in many cases, quaternary structure. They are long chains of amino acid units held together by peptide bonds, looped and folded into secondary and tertiary (and often quaternary) structures by disulfide bonds, hydrophobic interactions, and salt bridges.這樣我們能從蛋白質(zhì)一級(jí),二級(jí),三級(jí)和四級(jí)結(jié)構(gòu)方面來(lái)描述酶:它們是由氨基酸通過(guò)肽鍵結(jié)合的單位所組成,以纏繞折疊的方式,由二硫鍵,疏水鍵,鹽橋而構(gòu)成二級(jí)和三級(jí)結(jié)構(gòu)的許多長(zhǎng)鏈。9. In such instances, the enzyme without the cofactor is called an apoenzyme, and the apoenzymecofactor plex is called a holoenzyme. We will see that the protein chain of an apoenzyme can have functional groups on its side chains (R groups) which are important to its catalytic function, but other important functional groups are introduced by way of cofactors.有些時(shí)候,不含輔基的酶叫脫輔基蛋白酶,輔基和脫輔基蛋白酶的復(fù)合物叫全酶。我們將發(fā)現(xiàn)由脫輔基蛋白酶組成的蛋白質(zhì)鏈的側(cè)鏈上,具有對(duì)它的催化功能起重要作用的功能基團(tuán),但其他重要的功能基團(tuán)則是由催化劑的輔基提供。10. The fit can e about either because the molecule fits easily into the enzyme39。s active site (lockandkey model) or because the enzyme39。s structure adjusts to the substrate39。s entry (induced fit model). 匹配進(jìn)入酶的活性部位,要么因?yàn)檫@個(gè)分子容易進(jìn)入酶的活性部位,要么因?yàn)槊傅慕Y(jié)構(gòu)進(jìn)行調(diào)整。Lesson 1111. These provide the energy and building materials for the countless substances that are essential to the growth and survival of living things. The manner in which nutrients bee integral parts of the body and contribute to its function is dependent on the physiologic biochemical processes that govern their actions.這些營(yíng)養(yǎng)素為無(wú)數(shù)的生物生長(zhǎng)和生存所必需的物質(zhì)提供了能量和構(gòu)建物質(zhì)。在這種方式中,營(yíng)養(yǎng)素組成機(jī)體的有機(jī)部分,并依據(jù)控制他們行為的生理和生化過(guò)程,發(fā)揮他們的功能。12. As constituents of food we eat they not only provide energy but also
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