【正文】
regions of genes Investigation gene expression From genes to genomes Analysing genomes Mapping genomes Genome sequencing Sequencing technology Genome projects The human genome project Whose genome, and how many genes does it contain Geic and physical maps of the human genome Deriving and assembling the sequence What next? 本章要點(diǎn):掌握基因結(jié)構(gòu)與功能。了解基因組學(xué) 研究和人類基因組研究計(jì)劃。 Chapter 10 Geic engineering and biotechnology (2hrs) Making proteins Native and fusion proteins Yeast expression systems The baculovirus expression system Mammalian cell lines Protein engineering Examples of biotechnological applications of rDNA technology Production of enzymes The BST story Therapeutic products for use in human healthcare 本章要點(diǎn):掌握基因工程生產(chǎn)蛋白原理和方法。了解重組 DNA 技術(shù)的應(yīng)用事例。 Chapter 11 Medical and forensic applications of gene manipulation (1hrs) Diagnosis and characterization of medical conditions Diagnosis of infection Patters of inheritance Geically based disease conditions Treatment using rDNA technology— gene therapy Getting transgenes into patients Gene therapy for adenosine deaminase deficiency Gene therapy for cystic fibrosis DNA profiling The history of ‘geic fingerprinting’ DNA profiling and the law Mysteries of the past revealed by geic detectives 本章要點(diǎn):了解基因工程在醫(yī)藥上的應(yīng)用,了解基因診斷、基因治療和遺傳圖譜研究進(jìn)展。 Chapter 12 Transgenic Plants and animals (1hrs) Transgenic Plants Why transgenic plants? Tiplasmid as vectors for plant cells Making transgenic plants Putting the technology to work Transgenic animals Why transgenic animals Producing transgenic animals Applications of transgenic animal technology 本章要點(diǎn):了解 轉(zhuǎn)基因植物和轉(zhuǎn)基 因動(dòng)物的 應(yīng)用 。 Chapter 13 The other sort of cloning (1hrs) Early thoughts and experiments First steps towards cloning Nuclear totipotency Frogs and toad and carrots A famous sheep— the breakthrough achieved Beyond Dolly 本章要點(diǎn):了解“多莉羊”克隆技術(shù)及其意義。 Chapt