【正文】
lin granules (no membrane) lamellar granules. 3. Stratum Granulosum(顆粒層) : 4. Stratum Lucidum(透明層) : LM: Eosinophilic, transparent. EM: Matrix of keratohyalin granules+ embedded bundled . = keratin. 5. Stratum Corneum(角質(zhì)層) : LM: Acidophilic, continuously shed. EM: Full of keratin, thickened membrane, degenerated desmosomes (surface layers). Conclusion: The changes of the keratinized cells from Stratum basale to Stratum corneum show the process of the keratinization: ① Morphology: Columnar→ polygonal→ flattened。 ③ : → + → (exocytosis)。 ⑤ Keratin: → + → ++。 scattered→ bundle。 long branched processes. melanosome Tyrosine tyrosinase Melanin (黑色素) melanin granule full of melanin Function EM: melanosomes(黑素體) containing tyrosinase(酪氨酸) . Function: produce melanin granules which prevent ultraviolet radiation from damaging skin. (2) Langerhans cells(朗格漢斯細(xì)胞) : Location: among spinous cells ? LM: starshaped, lobed nucleus. ? Function: Identify, bind and process and present foreign antigens to lymphocytes. (3) Merkel cells(梅克爾細(xì)胞) : Location: among basal cells. Structure: dense granules, chemical synapse formed between the cell base and nerve ending. Function: perception of stimulation /mechanoreceptor. Me