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Effects of Intensive Blood Pressure Control in the Management of Patients With Type 2 Diabetes Mellitus in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial ACCORD Study Group. N Engl J Med March 14, 2020. Giuseppe Mancia. Circulation. 2020. JOSHUA ,et Care, 2020 ? 治療 1年后平均收縮壓比較:標(biāo)準(zhǔn)治療 強(qiáng)化治療 , δ= 強(qiáng)化治療降低收縮壓優(yōu)于標(biāo)準(zhǔn)治療 ACCORD Study Group. N Engl J Med March 14, 2020. 平均 SBP: 標(biāo)準(zhǔn)治療組 ;強(qiáng)化治療組 Comparison of CVD outes by level of central obesity in the ACCORD Blood Pressure Trial. 強(qiáng)化降壓降低卒中發(fā)生率,其余事件發(fā)生率組間無差異 強(qiáng)化治療嚴(yán)重不良事件發(fā)生率顯著增高 冠脈狹窄程度與心血管病事件殘余風(fēng)險(xiǎn) COURAGE study . John Mancini,et al. Circ Cardiovasc Interv. 2020 ? Angiographic Disease Progression and Residual Risk of Cardiovascular Events While on Optimal Medical Therapy Observations From the COURAGE (Clinical Outes Utilizing Revascularization and Aggressive Drug Evaluation) trial COURAGE study ? 接受最佳方案藥物治療( OMT)的冠心病穩(wěn)定性心絞痛患者,冠脈造影血管狹窄程度 < 50% VS ≥ 50%與心血管病事件殘余風(fēng)險(xiǎn)相關(guān)研究。 COURAGE試驗(yàn)啟示: ? 冠脈造影狹窄< 50%患者中有 1/3發(fā)生臨床癥狀而接受再次冠脈造影或干預(yù) ? 傳統(tǒng)冠脈造影 “ 金標(biāo)準(zhǔn) ” 挑戰(zhàn) ? 冠脈造影狹窄< 50%可能是重要?dú)堄囡L(fēng)險(xiǎn) ? The Risk of Thromboembolism ? and Need for Oral Anticoagulation ? After Successful Atrial Fibrillation Ablation ? Sakis Themistoclakis, MD,* Andrea Corrado, MD,* Francis E. Marchlinski, MD,? Pierre Jais, MD,? ? Erica Zado, PAC,? Antonio Rossillo, MD,* Luigi Di Biase, MD,167。 Rodney Horton, MD,167。 Dimpi Patel, DO,167。 Oussama M. Wazni, MD,182。 ? MestreVenice, Italy。 BordeauxPessac, France。 ? and Akron and Cleveland, Ohio ? Objectives The aim of this multicenter study was to evaluate the safety of discontinuing oral anticoagulation therapy (OAT) ? after apparently successful pulmonary vein isolation. ? Background Atrial fibrillation (AF) is associated with an increased risk of thromboembolic events (TE) and often requires OAT. ? Pulmonary vein isolation is considered an effective treatment for AF. ? Methods We studied 3,355