enrinology內(nèi)分泌總論-在線瀏覽
2024-07-10 01:40本頁面
【正文】 els should be evaluated in relation to the plasma glucose concentration, and PTH levels should be considered in relation to serum calcium levels. Clinical interpretation ? Since cortisol production integrated over a 24h period is increased in cushing’s syndrome, the 24h urinary free cortisol provides a more accurate index of cortisol hypersecretion. Clinical interpretation ? Sometimes the significance of hormone levels can be evaluated only by the simultaneous measurement of more than one hormone. ? For instance, with progressive damage to the thyroid hormones, secretion of TSH increases in a pensatory fashion so that normal plasma levels of the thyroid hormones may be maintained. GD的自身免疫發(fā)病機(jī)制 Clinical interpretation ? Plasma estrogens are low in ovarian failure. ? If ovarial failure is due to disease of the ovary, plasma gonadotropins will be elevated. ? If ovarian failure is secondary to pituitary or hypothalamic disease, plasma gonadotropin levels will be normal or decreased. Dynamic testing ? Provocative testing assesses the ability of a gland to respond to stimuli as an index of its reserve capacity. ? Insulin induced hypoglycemia is used to assess the secretory ability of cells that produce growth hormone. Tests that provide indirect information ? Diagnosis of diabetes mellitus and assessment of therapy depend on measurement of plasma glucose rather than insulin levels. ? It is helpful to follow the serum calcium levels in hyperparathyroidism and the serum potassium levels in primary aldosteronism. Tests that provide indirect information ? For instance, serum sodium is almost always greater than 139mEq/liter in patients with an aldosterone producing adenoma, plasma cholesterol tends to be high in hypothyroidism and low in hyperthyroidism. Treatment of endocrine and metabolic disease ? For endocrine deficiency syndromes, hormones are generally administered to counter the deficiency. ? Vitamin D is given instead of PTH to treat hypoparathyroidism, since it can increase the extracellular Ca+. ? In cases in which hormone resistance is present, steps are taken when possible to alleviate this, such as through diet restriction in type 2 diabetes. ? I
公司管理相關(guān)推薦
鄂ICP備17016276號-1